Positive effects of platelet-rich plasma (PRP) and a <i>Sanguisorba officinalis</i> polysaccharide on the proliferation and differentiation of anterior cruciate ligament (ACL) fibroblasts <i>in vitro</i>.

Zheng, Hong; Huang, Wenya; He, Bing; Tan, Hongchang; Lin, Pingzhi; Zha, Zhengang

Positive effects of platelet-rich plasma (PRP) and a Sanguisorba officinalis polysaccharide on the proliferation and differentiation of anterior cruciate ligament (ACL) fibroblasts in vitro.

Zheng, Hong; Huang, Wenya; He, Bing; Tan, Hongchang; Lin, Pingzhi; Zha, Zhengang.

Afiliación

Zheng H; Institute of Orthopedic Diseases and Department of Bone and Joint Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, China.
Huang W; Department of Orthopedic Surgery, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
He B; Department of Orthopedic Surgery, The People's Hospital of Leizhou, Leizhou, China.
Tan H; Department of Nursing, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
Lin P; Department of Orthopedic Surgery, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
Zha Z; Department of Orthopedic Surgery, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.

Pharm Biol ; 58(1): 297-305, 2020 Dec.

Article en En | MEDLINE | ID: mdl-32252578

Asunto(s)

Ligamento Cruzado Anterior/crecimiento & desarrollo; Ligamento Cruzado Anterior/metabolismo; Fibroblastos/efectos de los fármacos; Plasma Rico en Plaquetas/fisiología; Polisacáridos/química; Polisacáridos/farmacología; Sanguisorba/química; Animales; Apoptosis/efectos de los fármacos; Diferenciación Celular/efectos de los fármacos; Movimiento Celular/efectos de los fármacos; Proliferación Celular/efectos de los fármacos; Supervivencia Celular/efectos de los fármacos; Células Cultivadas; Colágeno/biosíntesis; Medicamentos Herbarios Chinos/farmacología; Fibroblastos/citología; Fibroblastos/metabolismo; Masculino; FN-kappa B/metabolismo; Raíces de Plantas/química; Polisacáridos/aislamiento & purificación; Conejos; Receptor Toll-Like 4/metabolismo

Palabras clave

Degenerative joint disease; TLR-4/NF-κB signalling pathway; apoptosis; migration and differentiation; osteoblastic proliferation

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Polisacáridos / Ligamento Cruzado Anterior / Sanguisorba / Plasma Rico en Plaquetas / Fibroblastos Límite: Animals Idioma: En Año: 2020 Tipo del documento: Article

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