[Research advances on adrenergic receptor signaling involved in disease microenvironment through regulation of macrophages].
Sheng Li Xue Bao
; 72(2): 227-234, 2020 Apr 25.
Article
en Zh
| MEDLINE
| ID: mdl-32328616
ABSTRACT
Adrenergic receptor (AR), one of the key receptors for nervous system, plays an important role in the immune microenvironment and the progression of many diseases. In recent years, the regulation of ARs and its signal on macrophages has become a research hotspot. Researchers found that ARs could exert different regulatory functions on macrophages in different microenvironments, which in turn affects occurrence and development of diseases such as tumor, heart failure, obesity, acute injury, infection and pregnancy-related diseases. This review summarizes the expression and functional regulation of ARs on macrophages, and the role of ARs in microenvironment of related diseases, which might provide new ideas for the treatments.
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Banco de datos:
MEDLINE
Asunto principal:
Transducción de Señal
/
Enfermedad
/
Receptores Adrenérgicos
/
Macrófagos
Límite:
Humans
Idioma:
Zh
Año:
2020
Tipo del documento:
Article