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Design, synthesis and biological evaluation of pyridine derivatives as selective SHP2 inhibitors.
Liu, Wen-Shan; Yang, Bing; Wang, Rui-Rui; Li, Wei-Ya; Ma, Yang-Chun; Zhou, Liang; Du, Shan; Ma, Ying; Wang, Run-Ling.
Afiliación
  • Liu WS; Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics (Theranostics), School of Pharmacy, Tianjin Medical University, Tianjin 300070, China; Department of Pharmacy, Affiliated Hospital of Weifang Medical University, Weifang, Shandong 261000, China.
  • Yang B; Department of Cell Biology, School of Basic Medical Science, Tianjin Medical University, Tianjin 300070, China.
  • Wang RR; Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics (Theranostics), School of Pharmacy, Tianjin Medical University, Tianjin 300070, China.
  • Li WY; Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics (Theranostics), School of Pharmacy, Tianjin Medical University, Tianjin 300070, China.
  • Ma YC; Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics (Theranostics), School of Pharmacy, Tianjin Medical University, Tianjin 300070, China.
  • Zhou L; Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics (Theranostics), School of Pharmacy, Tianjin Medical University, Tianjin 300070, China.
  • Du S; Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics (Theranostics), School of Pharmacy, Tianjin Medical University, Tianjin 300070, China.
  • Ma Y; Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics (Theranostics), School of Pharmacy, Tianjin Medical University, Tianjin 300070, China. Electronic address: maying@tmu.edu.cn.
  • Wang RL; Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics (Theranostics), School of Pharmacy, Tianjin Medical University, Tianjin 300070, China. Electronic address: wangrunling@tmu.edu.cn.
Bioorg Chem ; 100: 103875, 2020 07.
Article en En | MEDLINE | ID: mdl-32380342
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Piridinas / Inhibidores Enzimáticos / Proteína Tirosina Fosfatasa no Receptora Tipo 11 Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Año: 2020 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Piridinas / Inhibidores Enzimáticos / Proteína Tirosina Fosfatasa no Receptora Tipo 11 Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Año: 2020 Tipo del documento: Article