Creatine Transporter, Reduced in Colon Tissues From Patients With Inflammatory Bowel Diseases, Regulates Energy Balance in Intestinal Epithelial Cells, Epithelial Integrity, and Barrier Function.

Hall, Caroline H T; Lee, J Scott; Murphy, Emily M; Gerich, Mark E; Dran, Rachael; Glover, Louis E; Abdulla, Zuhair I; Skelton, Matthew R; Colgan, Sean P

Hall, Caroline H T; Lee, J Scott; Murphy, Emily M; Gerich, Mark E; Dran, Rachael; Glover, Louis E; Abdulla, Zuhair I; Skelton, Matthew R; Colgan, Sean P.

Afiliación

Hall CHT; Division of Gastroenterology, Hepatology and Nutrition, Children's Hospital Colorado, Aurora, Colorado; Mucosal Inflammation Program, University of Colorado, Aurora, Colorado.
Lee JS; Mucosal Inflammation Program, University of Colorado, Aurora, Colorado; Division of Gastroenterology and Hepatology, University of Colorado, Aurora, Colorado.
Murphy EM; Division of Gastroenterology, Hepatology and Nutrition, Children's Hospital Colorado, Aurora, Colorado; Mucosal Inflammation Program, University of Colorado, Aurora, Colorado; Division of Gastroenterology and Hepatology, University of Colorado, Aurora, Colorado.
Gerich ME; Mucosal Inflammation Program, University of Colorado, Aurora, Colorado; Division of Gastroenterology and Hepatology, University of Colorado, Aurora, Colorado.
Dran R; Mucosal Inflammation Program, University of Colorado, Aurora, Colorado; Division of Gastroenterology and Hepatology, University of Colorado, Aurora, Colorado.
Glover LE; Mucosal Inflammation Program, University of Colorado, Aurora, Colorado; Division of Gastroenterology and Hepatology, University of Colorado, Aurora, Colorado; School of Biochemistry and Immunology, Trinity College Dublin, Ireland.
Abdulla ZI; Department of Pediatrics, University of Cincinnati, Cincinnati, Ohio; Division of Neurology, Cincinnati Children's Research Foundation, Cincinnati, Ohio.
Skelton MR; Department of Pediatrics, University of Cincinnati, Cincinnati, Ohio; Division of Neurology, Cincinnati Children's Research Foundation, Cincinnati, Ohio.
Colgan SP; Mucosal Inflammation Program, University of Colorado, Aurora, Colorado; Division of Gastroenterology and Hepatology, University of Colorado, Aurora, Colorado. Electronic address: sean.colgan@ucdenver.edu.

Gastroenterology ; 159(3): 984-998.e1, 2020 09.

Article en En | MEDLINE | ID: mdl-32433978

Asunto(s)

Colitis Ulcerosa/patología; Colon/patología; Enfermedad de Crohn/patología; Mucosa Intestinal/patología; Proteínas de Transporte de Membrana/metabolismo; Proteínas del Tejido Nervioso/metabolismo; Proteínas de Transporte de Neurotransmisores en la Membrana Plasmática/metabolismo; Adulto; Animales; Biopsia; Estudios de Casos y Controles; Línea Celular; Metabolismo Energético; Células Epiteliales/citología; Células Epiteliales/patología; Femenino; Técnicas de Silenciamiento del Gen; Humanos; Masculino; Proteínas de Transporte de Membrana/genética; Ratones; Ratones Noqueados; Persona de Mediana Edad; Mitocondrias/metabolismo; Proteínas del Tejido Nervioso/genética; Proteínas de Transporte de Neurotransmisores en la Membrana Plasmática/genética; Uniones Estrechas/patología

Palabras clave

Actin; CD; Claudin; UC

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas de Transporte de Membrana / Colitis Ulcerosa / Enfermedad de Crohn / Colon / Proteínas de Transporte de Neurotransmisores en la Membrana Plasmática / Mucosa Intestinal / Proteínas del Tejido Nervioso Límite: Adult / Animals / Female / Humans / Male / Middle aged Idioma: En Año: 2020 Tipo del documento: Article

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