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Epitope and Paratope Mapping of PD-1/Nivolumab by Mass Spectrometry-Based Hydrogen-Deuterium Exchange, Cross-linking, and Molecular Docking.
Zhang, Mengru Mira; Huang, Richard Y-C; Beno, Brett R; Deyanova, Ekaterina G; Li, Jing; Chen, Guodong; Gross, Michael L.
Afiliación
  • Zhang MM; Department of Chemistry, Washington University, St. Louis, Missouri 63130, United States.
  • Huang RY; Pharmaceutical Candidate Optimization, Nonclinical Research and Development, Bristol Myers Squibb Company, Princeton, New Jersey 08540, United States.
  • Beno BR; Molecular Structure & Design, Small Molecule Drug Discovery, Bristol Myers Squibb Company, Princeton, New Jersey 08540, United States.
  • Deyanova EG; Pharmaceutical Candidate Optimization, Nonclinical Research and Development, Bristol Myers Squibb Company, Princeton, New Jersey 08540, United States.
  • Li J; Pharmaceutical Candidate Optimization, Nonclinical Research and Development, Bristol Myers Squibb Company, Princeton, New Jersey 08540, United States.
  • Chen G; Pharmaceutical Candidate Optimization, Nonclinical Research and Development, Bristol Myers Squibb Company, Princeton, New Jersey 08540, United States.
  • Gross ML; Department of Chemistry, Washington University, St. Louis, Missouri 63130, United States.
Anal Chem ; 92(13): 9086-9094, 2020 07 07.
Article en En | MEDLINE | ID: mdl-32441507
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Mapeo Epitopo / Medición de Intercambio de Deuterio / Receptor de Muerte Celular Programada 1 / Nivolumab / Epítopos Límite: Humans Idioma: En Año: 2020 Tipo del documento: Article
Texto completo
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XML
PubMed Links
Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Mapeo Epitopo / Medición de Intercambio de Deuterio / Receptor de Muerte Celular Programada 1 / Nivolumab / Epítopos Límite: Humans Idioma: En Año: 2020 Tipo del documento: Article