Reactive Arthritis: Treatment Challenges and Future Perspectives.
Curr Rheumatol Rep
; 22(7): 29, 2020 05 26.
Article
en En
| MEDLINE
| ID: mdl-32458153
ABSTRACT
PURPOSE OF THE REVIEW Reactive arthritis is synovitis related to an infection away from the joint. The evolution is variable, frequently self-limited, but with the possible evolution to a prolonged form, generating functional incapacity and sequelae. RECENT FINDINGS:
New microbiological families have been incriminated and pathophysiological links have been clarified, highlighting the role of the mucous membranes (gut in particular), specific cell populations, and the production of pro-inflammatory cytokines. First-line pharmacological treatment is based on NSAIDs. In case of failure, synthetic and more recently biological DMARDs are indicated. Only open data are available for biological DMARDs but suggest good efficacy and safety. Reactive arthritis has not disappeared. The diagnosis must be mentioned by the clinic and history to allow the rapid introduction of an appropriate treatment.Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Sinovitis
/
Artritis Reactiva
/
Antirreumáticos
Tipo de estudio:
Diagnostic_studies
Límite:
Humans
Idioma:
En
Año:
2020
Tipo del documento:
Article