Tp0136 targets fibronectin (RGD)/Integrin ß1 interactions promoting human microvascular endothelial cell migration.

Luo, Xi; Lin, Shu-Wen; Xu, Qiu-Yan; Ke, Wu-Jian; Gao, Zheng-Xiang; Tong, Man-Li; Liu, Li-Li; Lin, Li-Rong; Zhang, Hui-Lin; Yang, Tian-Ci

Luo, Xi; Lin, Shu-Wen; Xu, Qiu-Yan; Ke, Wu-Jian; Gao, Zheng-Xiang; Tong, Man-Li; Liu, Li-Li; Lin, Li-Rong; Zhang, Hui-Lin; Yang, Tian-Ci.

Afiliación

Luo X; Center of Clinical Laboratory, Zhongshan Hospital, School of Medicine, Xiamen University, Xiamen, 361004, China.
Lin SW; Clinical Laboratory, Xiamen Children's Hospital, Children's Hospital of Fudan University Xiamen Branch, Xiamen, 361006, China.
Xu QY; Center of Clinical Laboratory, Zhongshan Hospital, School of Medicine, Xiamen University, Xiamen, 361004, China.
Ke WJ; Dermatology Hospital, Southern Medical University, Guangzhou, 510091, China.
Gao ZX; Center of Clinical Laboratory, Zhongshan Hospital, School of Medicine, Xiamen University, Xiamen, 361004, China.
Tong ML; Center of Clinical Laboratory, Zhongshan Hospital, School of Medicine, Xiamen University, Xiamen, 361004, China; Institute of Infectious Disease, School of Medicine, Xiamen University, Xiamen, 361004, China.
Liu LL; Center of Clinical Laboratory, Zhongshan Hospital, School of Medicine, Xiamen University, Xiamen, 361004, China; Institute of Infectious Disease, School of Medicine, Xiamen University, Xiamen, 361004, China.
Lin LR; Center of Clinical Laboratory, Zhongshan Hospital, School of Medicine, Xiamen University, Xiamen, 361004, China; Institute of Infectious Disease, School of Medicine, Xiamen University, Xiamen, 361004, China.
Zhang HL; Center of Clinical Laboratory, Zhongshan Hospital, School of Medicine, Xiamen University, Xiamen, 361004, China; Institute of Infectious Disease, School of Medicine, Xiamen University, Xiamen, 361004, China. Electronic address: zhanghuilin@xmu.edu.cn.
Yang TC; Center of Clinical Laboratory, Zhongshan Hospital, School of Medicine, Xiamen University, Xiamen, 361004, China; Institute of Infectious Disease, School of Medicine, Xiamen University, Xiamen, 361004, China. Electronic address: yangtianci@xmu.edu.cn.

Exp Cell Res ; 396(1): 112289, 2020 11 01.

Article en En | MEDLINE | ID: mdl-32950474

Asunto(s)

Proteínas Bacterianas/farmacología; Movimiento Celular/efectos de los fármacos; Fibronectinas/genética; Integrina beta1/genética; Treponema pallidum/metabolismo; Anticuerpos Neutralizantes/farmacología; Proteínas Bacterianas/genética; Proteínas Bacterianas/metabolismo; Línea Celular; Quimiocina CCL2/genética; Quimiocina CCL2/metabolismo; Clonación Molecular; Células Endoteliales/metabolismo; Células Endoteliales/microbiología; Escherichia coli/genética; Escherichia coli/metabolismo; Fibronectinas/antagonistas & inhibidores; Fibronectinas/metabolismo; Expresión Génica; Regulación de la Expresión Génica; Vectores Genéticos/química; Vectores Genéticos/metabolismo; Interacciones Huésped-Patógeno/genética; Humanos; Integrina beta1/metabolismo; Oligopéptidos/farmacología; Unión Proteica; Receptores CCR2/genética; Receptores CCR2/metabolismo; Proteínas Recombinantes/genética; Proteínas Recombinantes/metabolismo; Proteínas Recombinantes/farmacología; Transducción de Señal; Treponema pallidum/química

Palabras clave

CCL2; Fibronectin; Integrin ß1; Migration; RGD; Tp0136

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas Bacterianas / Treponema pallidum / Movimiento Celular / Fibronectinas / Integrina beta1 Límite: Humans Idioma: En Año: 2020 Tipo del documento: Article

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