Hepatocyte Nuclear Factor 4&#945; Prevents the Steatosis-to-NASH Progression by Regulating p53 and Bile Acid Signaling (in mice).

Xu, Yanyong; Zhu, Yingdong; Hu, Shuwei; Xu, Yang; Stroup, Diane; Pan, Xiaoli; Bawa, Fathima Cassim; Chen, Shaoru; Gopoju, Raja; Yin, Liya; Zhang, Yanqiao

Hepatocyte Nuclear Factor 4α Prevents the Steatosis-to-NASH Progression by Regulating p53 and Bile Acid Signaling (in mice).

Xu, Yanyong; Zhu, Yingdong; Hu, Shuwei; Xu, Yang; Stroup, Diane; Pan, Xiaoli; Bawa, Fathima Cassim; Chen, Shaoru; Gopoju, Raja; Yin, Liya; Zhang, Yanqiao.

Afiliación

Xu Y; Department of Integrative Medical Sciences, Northeast Ohio Medical University, Rootstown, OH.
Zhu Y; Department of Integrative Medical Sciences, Northeast Ohio Medical University, Rootstown, OH.
Hu S; Department of Integrative Medical Sciences, Northeast Ohio Medical University, Rootstown, OH.
Xu Y; Department of Integrative Medical Sciences, Northeast Ohio Medical University, Rootstown, OH.
Stroup D; Department of Chemistry and Biochemistry, Kent State University, Kent, OH.
Pan X; Department of Integrative Medical Sciences, Northeast Ohio Medical University, Rootstown, OH.
Bawa FC; Department of Integrative Medical Sciences, Northeast Ohio Medical University, Rootstown, OH.
Chen S; Department of Integrative Medical Sciences, Northeast Ohio Medical University, Rootstown, OH.
Gopoju R; Department of Integrative Medical Sciences, Northeast Ohio Medical University, Rootstown, OH.
Yin L; Department of Integrative Medical Sciences, Northeast Ohio Medical University, Rootstown, OH.
Zhang Y; Department of Integrative Medical Sciences, Northeast Ohio Medical University, Rootstown, OH.

Hepatology ; 73(6): 2251-2265, 2021 06.

Article en En | MEDLINE | ID: mdl-33098092

Asunto(s)

Ácidos y Sales Biliares/metabolismo; Dieta Alta en Grasa; Factor Nuclear 4 del Hepatocito/metabolismo; Hepatocitos/metabolismo; Hígado/metabolismo; Enfermedad del Hígado Graso no Alcohólico/prevención & control; Proteína p53 Supresora de Tumor/metabolismo; Animales; Ácido Quenodesoxicólico/análogos & derivados; Ácido Quenodesoxicólico/farmacología; Colesterol 7-alfa-Hidroxilasa/metabolismo; Factor Nuclear 4 del Hepatocito/genética; Hepatocitos/patología; Hígado/patología; Masculino; Ratones; Ratones Endogámicos C57BL; Enfermedad del Hígado Graso no Alcohólico/genética; Enfermedad del Hígado Graso no Alcohólico/metabolismo; Transducción de Señal; Esteroide 12-alfa-Hidroxilasa/metabolismo; Triglicéridos/sangre; Proteína p53 Supresora de Tumor/genética

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Ácidos y Sales Biliares / Proteína p53 Supresora de Tumor / Hepatocitos / Factor Nuclear 4 del Hepatocito / Dieta Alta en Grasa / Enfermedad del Hígado Graso no Alcohólico / Hígado Límite: Animals Idioma: En Año: 2021 Tipo del documento: Article

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