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Hematoxylin binds to mutant calreticulin and disrupts its abnormal interaction with thrombopoietin receptor.
Jia, Ruochen; Balligand, Thomas; Atamanyuk, Vasyl; Nivarthi, Harini; Xu, Erica; Kutzner, Leon; Weinzierl, Jakob; Nedelec, Audrey; Kubicek, Stefan; Lesyk, Roman; Zagrijtschuk, Oleh; Constantinescu, Stefan N; Kralovics, Robert.
Afiliación
  • Jia R; Department of Laboratory Medicine, Medical University of Vienna, Vienna, Austria.
  • Balligand T; CeMM Research Center for Molecular Medicine, Austrian Academy of Sciences, Vienna, Austria.
  • Atamanyuk V; Ludwig Cancer Research, de Duve Institute, Université Catholique de Louvain Brussels, Brussels, Belgium.
  • Nivarthi H; WELBIO (Walloon Excellence in Life Sciences and Biotechnology), Brussels, Belgium.
  • Xu E; Department of Pharmaceutical, Organic and Bioorganic Chemistry, Danylo Halytsky Lviv National Medical University, Lviv, Ukraine.
  • Kutzner L; Department of Laboratory Medicine, Medical University of Vienna, Vienna, Austria.
  • Weinzierl J; CeMM Research Center for Molecular Medicine, Austrian Academy of Sciences, Vienna, Austria.
  • Nedelec A; MyeloPro Diagnostics and Research GmbH, Vienna, Austria.
  • Kubicek S; CeMM Research Center for Molecular Medicine, Austrian Academy of Sciences, Vienna, Austria.
  • Lesyk R; Department of Laboratory Medicine, Medical University of Vienna, Vienna, Austria.
  • Zagrijtschuk O; Ludwig Cancer Research, de Duve Institute, Université Catholique de Louvain Brussels, Brussels, Belgium.
  • Constantinescu SN; WELBIO (Walloon Excellence in Life Sciences and Biotechnology), Brussels, Belgium.
  • Kralovics R; CeMM Research Center for Molecular Medicine, Austrian Academy of Sciences, Vienna, Austria.
Blood ; 137(14): 1920-1931, 2021 04 08.
Article en En | MEDLINE | ID: mdl-33202418
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Calreticulina / Receptores de Trombopoyetina / Mapas de Interacción de Proteínas / Hematoxilina Límite: Animals / Humans Idioma: En Año: 2021 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Calreticulina / Receptores de Trombopoyetina / Mapas de Interacción de Proteínas / Hematoxilina Límite: Animals / Humans Idioma: En Año: 2021 Tipo del documento: Article