Successful Unilateral Surgical Approach to Internal Globus Pallidus and Ventral Intermediate Nucleus of the Thalamus in 3 Cases of Myoclonus-Dystonia Syndrome.
Stereotact Funct Neurosurg
; 99(3): 250-255, 2021.
Article
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| MEDLINE
| ID: mdl-33242869
ABSTRACT
Surgical approaches of internal globus pallidus (GPi) and ventral intermediate thalamic nucleus (Vim) have been used to treat different movement disorders. Three subjects with myoclonus-dystonia syndrome were surgically treated, one of them with GPi and Vim stimulation, while radiofrequency ablation of these structures was performed in the other 2 subjects. Surgical approach of both targets was performed simultaneously on each subject. Mean follow-up was of 33.3 months (22-48 months), the Unified Myoclonus Rating Scale action myoclonus (AM), functional tests (FT), patient questionnaire (PQ) sub-scores, and the Unified Dystonia Rating Scale (UDRS) were used during assessments. Improvement in all scales were seen 6 months after surgery (AM 74%, FT 60%, PQ 63%, UDRS 65%), and this benefit persisted throughout follow-up (AM 61%, FT62%, PQ 65%, UDRS 86%). No adverse events were noticed. Simultaneous unilateral procedures of GPi and Vim by either stimulation or ablation techniques improve both motor and functional scores in myoclonus-dystonia syndrome.
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MEDLINE
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Trastornos Distónicos
/
Estimulación Encefálica Profunda
Límite:
Humans
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En
Año:
2021
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Article