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Intravesical nadofaragene firadenovec gene therapy for BCG-unresponsive non-muscle-invasive bladder cancer: a single-arm, open-label, repeat-dose clinical trial.
Boorjian, Stephen A; Alemozaffar, Mehrdad; Konety, Badrinath R; Shore, Neal D; Gomella, Leonard G; Kamat, Ashish M; Bivalacqua, Trinity J; Montgomery, Jeffrey S; Lerner, Seth P; Busby, Joseph E; Poch, Michael; Crispen, Paul L; Steinberg, Gary D; Schuckman, Anne K; Downs, Tracy M; Svatek, Robert S; Mashni, Joseph; Lane, Brian R; Guzzo, Thomas J; Bratslavsky, Gennady; Karsh, Lawrence I; Woods, Michael E; Brown, Gordon; Canter, Daniel; Luchey, Adam; Lotan, Yair; Krupski, Tracey; Inman, Brant A; Williams, Michael B; Cookson, Michael S; Keegan, Kirk A; Andriole, Gerald L; Sankin, Alexander I; Boyd, Alan; O'Donnell, Michael A; Sawutz, David; Philipson, Richard; Coll, Ruth; Narayan, Vikram M; Treasure, F Peter; Yla-Herttuala, Seppo; Parker, Nigel R; Dinney, Colin P N.
Afiliación
  • Boorjian SA; Department of Urology, Mayo Clinic, Rochester, MN, USA.
  • Alemozaffar M; Department of Urology, Kaiser Permanente Los Angeles, Los Angeles, CA, USA.
  • Konety BR; Department of Urology, University of Minnesota, Minneapolis, MN, USA.
  • Shore ND; Carolina Urologic Research Center, Myrtle Beach, SC, USA.
  • Gomella LG; Department of Urology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA, USA.
  • Kamat AM; Department of Urology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Bivalacqua TJ; Department of Urology, The James Buchanan Brady Urological Institute, Johns Hopkins School of Medicine, Baltimore, MD, USA.
  • Montgomery JS; Department of Urology, University of Michigan, Ann Arbor, MI, USA.
  • Lerner SP; Scott Department of Urology, Dan L Duncan Cancer Center, Baylor College of Medicine, Houston, TX, USA.
  • Busby JE; Cancer Centers of the Carolinas, Greenville Hospital System, Greenville, SC, USA.
  • Poch M; Department of GU Oncology, H Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA.
  • Crispen PL; Department of Urology, University of Florida, Gainesville, FL, USA.
  • Steinberg GD; Department of Urology, New York University Langone Health, New York, NY, USA.
  • Schuckman AK; USC Institute of Urology, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA, USA.
  • Downs TM; Department of Urology, University of Wisconsin, Madison, WI, USA.
  • Svatek RS; Department of Urology, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.
  • Mashni J; Banner MD Anderson Cancer Center, Gilbert, AZ, USA.
  • Lane BR; Division of Urology, Spectrum Health, Michigan State University College of Human Medicine, Grand Rapids, MI, USA.
  • Guzzo TJ; Division of Urology, University of Pennsylvania, Philadelphia, PA, USA.
  • Bratslavsky G; Department of Urology, SUNY Upstate Medical University, Syracuse, NY, USA.
  • Karsh LI; The Urology Center of Colorado, Denver, CO, USA.
  • Woods ME; Department of Urology, University of North Carolina, Chapel Hill, NC, USA.
  • Brown G; New Jersey Urology, Bloomfield, NJ, USA.
  • Canter D; Ochsner Health System, Jefferson, LA, USA.
  • Luchey A; West Virginia University Cancer Institute, Morgantown, WV, USA.
  • Lotan Y; Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Krupski T; Department of Urology, University of Virginia Cancer Center, Charlottesville, VA, USA.
  • Inman BA; Division of Urology, Department of Surgery, Duke University School of Medicine, Durham, NC, USA.
  • Williams MB; Urology of Virginia, Virginia Beach, VA, USA.
  • Cookson MS; Department of Urology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
  • Keegan KA; Department of Urology, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Andriole GL; Washington University School of Medicine in St Louis, St Louis, MO, USA.
  • Sankin AI; Department of Urology, Montefiore Medical Center, Bronx, NY, USA.
  • Boyd A; Alan Boyd Consultants, Crewe, UK.
  • O'Donnell MA; Department of Urology, University of Iowa, Iowa City, IA, USA.
  • Sawutz D; FKD Therapies Oy, Kuopio, Finland.
  • Philipson R; Trizell, Chinnor, Oxon, UK.
  • Coll R; Trizell, Chinnor, Oxon, UK.
  • Narayan VM; Department of Urology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Treasure FP; Peter Treasure Statistical Services, King's Lynn, UK.
  • Yla-Herttuala S; AI Virtanen Institute University of Eastern Finland and Science Service Center and Gene Therapy Unit, Kuopio, Finland.
  • Parker NR; AI Virtanen Institute University of Eastern Finland and Science Service Center and Gene Therapy Unit, Kuopio, Finland.
  • Dinney CPN; Department of Urology, University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address: cdinney@mdanderson.org.
Lancet Oncol ; 22(1): 107-117, 2021 01.
Article en En | MEDLINE | ID: mdl-33253641

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias de la Vejiga Urinaria / Vacuna BCG / Carcinoma in Situ / Terapia Genética / Adenoviridae / Resistencia a Antineoplásicos / Interferón alfa-2 / Vectores Genéticos Tipo de estudio: Clinical_trials / Guideline Límite: Aged / Female / Humans / Male / Middle aged País/Región como asunto: America do norte Idioma: En Año: 2021 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias de la Vejiga Urinaria / Vacuna BCG / Carcinoma in Situ / Terapia Genética / Adenoviridae / Resistencia a Antineoplásicos / Interferón alfa-2 / Vectores Genéticos Tipo de estudio: Clinical_trials / Guideline Límite: Aged / Female / Humans / Male / Middle aged País/Región como asunto: America do norte Idioma: En Año: 2021 Tipo del documento: Article