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Paracetamol analogues conjugated by FAAH induce TRPV1-mediated antinociception without causing acute liver toxicity.
Å Nilsson, Johan L; Mallet, Christophe; Shionoya, Kiseko; Blomgren, Anders; Sundin, Anders P; Grundemar, Lars; Boudieu, Ludivine; Blomqvist, Anders; Eschalier, Alain; Nilsson, Ulf J; Zygmunt, Peter M.
Afiliación
  • Å Nilsson JL; Division of Clinical Chemistry and Pharmacology, Department of Laboratory Medicine, Lund University, Box 117, SE-221 00, Lund, Sweden.
  • Mallet C; Université Clermont Auvergne, INSERM, NEURO-DOL Basics & Clinical Pharmacology of Pain, F-63000, Clermont-Ferrand, France; ANALGESIA Institute, Faculty of Medicine, F-63000, Clermont-Ferrand, France.
  • Shionoya K; Division of Neurobiology, Department of Biomedical and Clinical Sciences, Linköping University, SE-581 85, Linköping, Sweden.
  • Blomgren A; Division of Clinical Chemistry and Pharmacology, Department of Laboratory Medicine, Lund University, Box 117, SE-221 00, Lund, Sweden.
  • Sundin AP; Centre for Analysis and Synthesis, Department of Chemistry, Lund University, 221 00, Lund, Sweden.
  • Grundemar L; Division of Clinical Chemistry and Pharmacology, Department of Laboratory Medicine, Lund University, Box 117, SE-221 00, Lund, Sweden.
  • Boudieu L; Université Clermont Auvergne, INSERM, NEURO-DOL Basics & Clinical Pharmacology of Pain, F-63000, Clermont-Ferrand, France; ANALGESIA Institute, Faculty of Medicine, F-63000, Clermont-Ferrand, France.
  • Blomqvist A; Division of Neurobiology, Department of Biomedical and Clinical Sciences, Linköping University, SE-581 85, Linköping, Sweden.
  • Eschalier A; Université Clermont Auvergne, INSERM, NEURO-DOL Basics & Clinical Pharmacology of Pain, F-63000, Clermont-Ferrand, France; ANALGESIA Institute, Faculty of Medicine, F-63000, Clermont-Ferrand, France.
  • Nilsson UJ; Centre for Analysis and Synthesis, Department of Chemistry, Lund University, 221 00, Lund, Sweden.
  • Zygmunt PM; Department of Clinical Sciences Malmö, Lund University, SE-214 28, Malmö, Sweden. Electronic address: peter.zygmunt@med.lu.se.
Eur J Med Chem ; 213: 113042, 2021 Mar 05.
Article en En | MEDLINE | ID: mdl-33257173
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Canales de Potencial de Receptor Transitorio / Canales Catiónicos TRPV / Antipiréticos / Amidohidrolasas / Analgésicos / Acetaminofén Límite: Animals / Female / Humans / Male Idioma: En Año: 2021 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Canales de Potencial de Receptor Transitorio / Canales Catiónicos TRPV / Antipiréticos / Amidohidrolasas / Analgésicos / Acetaminofén Límite: Animals / Female / Humans / Male Idioma: En Año: 2021 Tipo del documento: Article