Early use of continuous glucose monitoring in children and adolescents after total pancreatectomy with islet autotransplantation.
Pediatr Diabetes
; 22(3): 434-438, 2021 05.
Article
en En
| MEDLINE
| ID: mdl-33271633
ABSTRACT
BACKGROUND:
Children undergoing total pancreatectomy with islet autotransplantation (TPIAT) for chronic pancreatitis require intensive insulin therapy early after TPIAT with narrow glycemic targets, which can a present significant care burden. Outpatient use of continuous glucose monitoring (CGM) systems by children and caregivers early after TPIAT is inadequately studied.METHODS:
In this open-label study, we randomized 14 children and adolescents (mean age 15.4 years) after hospital discharge for TPIAT to Dexcom G6 CGM (n = 7) or standard care with a glucometer (n = 7) to assess acceptability and glycemic control with use of CGM versus usual care (glucometer). Participants in the control arm also wore a blinded CGM for 1 week.RESULT:
Children randomized to real-time CGM had lower mean sensor glucose values compared with controls (p = 0.002), and high overall satisfaction with CGM.CONCLUSIONS:
Our data indicate that CGM is a useful adjunct to diabetes management for children who have recently undergone TPIAT.Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Pancreatectomía
/
Automonitorización de la Glucosa Sanguínea
/
Trasplante de Islotes Pancreáticos
/
Pancreatitis Crónica
/
Control Glucémico
Tipo de estudio:
Clinical_trials
Límite:
Adolescent
/
Child
/
Female
/
Humans
/
Male
Idioma:
En
Año:
2021
Tipo del documento:
Article