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Novel tankyrase inhibitors suppress TDP-43 aggregate formation.
Tanji, Kunikazu; Mori, Fumiaki; Shirai, Fumiyuki; Fukami, Takehiro; Seimiya, Hiroyuki; Utsumi, Jun; Kakita, Akiyoshi; Wakabayashi, Koichi.
Afiliación
  • Tanji K; Department of Neuropathology, Institute of Brain Science, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki, Aomori, 036-8562, Japan. Electronic address: kunikazu@hirosaki-u.ac.jp.
  • Mori F; Department of Neuropathology, Institute of Brain Science, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki, Aomori, 036-8562, Japan.
  • Shirai F; Drug Discovery Chemistry Platform Unit, RIKEN Center for Sustainable Resource Science, RIKEN Cluster for Industry Partnerships, 2-1 Hirosawa, Wako, Saitama, 351-0198, Japan; Program for Drug Discovery and Medical Technology Platforms, RIKEN Cluster for Industry Partnerships, 2-1 Hirosawa, Wako, Sait
  • Fukami T; Program for Drug Discovery and Medical Technology Platforms, RIKEN Cluster for Industry Partnerships, 2-1 Hirosawa, Wako, Saitama, 351-0198, Japan.
  • Seimiya H; Cancer Chemotherapy Center, Japanese Foundation for Cancer Research, 3-8-31 Ariake, Koto-ku, Tokyo, 135-8550, Japan.
  • Utsumi J; Cancer Chemotherapy Center, Japanese Foundation for Cancer Research, 3-8-31 Ariake, Koto-ku, Tokyo, 135-8550, Japan.
  • Kakita A; Department of Pathology, Brain Research Institute, Niigata University, Niigata, 951-8585, Japan.
  • Wakabayashi K; Department of Neuropathology, Institute of Brain Science, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki, Aomori, 036-8562, Japan.
Biochem Biophys Res Commun ; 537: 85-92, 2021 01 22.
Article en En | MEDLINE | ID: mdl-33387887
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Tanquirasas / Proteínas de Unión al ADN / Inhibidores Enzimáticos / Agregado de Proteínas Límite: Humans Idioma: En Año: 2021 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Tanquirasas / Proteínas de Unión al ADN / Inhibidores Enzimáticos / Agregado de Proteínas Límite: Humans Idioma: En Año: 2021 Tipo del documento: Article