High-resolution melting effectively pre-screens for TP53 mutations before direct sequencing in patients with diffuse glioma.

Saito, Kiyotaka; Yokogami, Kiyotaka; Maekawa, Kazunari; Sato, Yuichiro; Yamashita, Shinji; Matsumoto, Fumitaka; Mizuguchi, Asako; Takeshima, Hideo

Saito, Kiyotaka; Yokogami, Kiyotaka; Maekawa, Kazunari; Sato, Yuichiro; Yamashita, Shinji; Matsumoto, Fumitaka; Mizuguchi, Asako; Takeshima, Hideo.

Afiliación

Saito K; Division of Clinical Neuroscience, Department of Neurosurgery, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake-cho, Miyazaki, 889-1692, Japan. kiyotaka_saitou@med.miyazaki-u.ac.jp.
Yokogami K; Division of Clinical Neuroscience, Department of Neurosurgery, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake-cho, Miyazaki, 889-1692, Japan.
Maekawa K; Department of Diagnostic Pathology, Miyazaki University Hospital, 5200 Kihara, Kiyotake-cho, Miyazaki, 889-1692, Japan.
Sato Y; Department of Diagnostic Pathology, Miyazaki University Hospital, 5200 Kihara, Kiyotake-cho, Miyazaki, 889-1692, Japan.
Yamashita S; Division of Clinical Neuroscience, Department of Neurosurgery, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake-cho, Miyazaki, 889-1692, Japan.
Matsumoto F; Division of Clinical Neuroscience, Department of Neurosurgery, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake-cho, Miyazaki, 889-1692, Japan.
Mizuguchi A; Division of Clinical Neuroscience, Department of Neurosurgery, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake-cho, Miyazaki, 889-1692, Japan.
Takeshima H; Division of Clinical Neuroscience, Department of Neurosurgery, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake-cho, Miyazaki, 889-1692, Japan.

Hum Cell ; 34(2): 644-653, 2021 Mar.

Article en En | MEDLINE | ID: mdl-33454902

Asunto(s)

Astrocitoma/genética; Neoplasias Encefálicas/genética; Análisis Mutacional de ADN/métodos; Pruebas Genéticas/métodos; Glioblastoma/genética; Mutación; Proteína p53 Supresora de Tumor/genética; Dermatitis Alérgica por Contacto; Exones/genética; Humanos; Inmunohistoquímica; Metacrilatos/efectos adversos; Mutación Missense; Proteína p53 Supresora de Tumor/metabolismo

Palabras clave

Diffuse glioma; High-resolution melting; Immunohistochemistry; TP53 mutation; p53

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Astrocitoma / Neoplasias Encefálicas / Análisis Mutacional de ADN / Pruebas Genéticas / Proteína p53 Supresora de Tumor / Glioblastoma / Mutación Límite: Humans Idioma: En Año: 2021 Tipo del documento: Article

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