Insights into structural and physicochemical properties required for ß-hematin inhibition of privileged triarylimidazoles.

Veale, Clinton G L; Jayram, Janeeka; Naidoo, Shivani; Laming, Dustin; Swart, Tarryn; Olivier, Tania; Akerman, Matthew P; de Villiers, Katherine A; Hoppe, Heinrich C; Jeena, Vineet.

Afiliación

Veale CGL; School of Chemistry and Physics , Pietermaritzburg Campus , University of KwaZulu-Natal , Private Bag X01 , Scottsville , 3209 , South Africa.
Jayram J; School of Chemistry and Physics , Pietermaritzburg Campus , University of KwaZulu-Natal , Private Bag X01 , Scottsville , 3209 , South Africa.
Naidoo S; School of Chemistry and Physics , Pietermaritzburg Campus , University of KwaZulu-Natal , Private Bag X01 , Scottsville , 3209 , South Africa.
Laming D; Department of Biochemistry and Microbiology , Rhodes University , Grahamstown , 6140 , South Africa.
Swart T; Department of Biochemistry and Microbiology , Rhodes University , Grahamstown , 6140 , South Africa.
Olivier T; Department of Chemistry and Polymer Science , Stellenbosch University , Private Bag X1 , Matieland , 7602 , South Africa . Email: VealeC@ukzn.ac.za ; Email: JeenaV1@ukzn.ac.za.
Akerman MP; School of Chemistry and Physics , Pietermaritzburg Campus , University of KwaZulu-Natal , Private Bag X01 , Scottsville , 3209 , South Africa.
de Villiers KA; Department of Chemistry and Polymer Science , Stellenbosch University , Private Bag X1 , Matieland , 7602 , South Africa . Email: VealeC@ukzn.ac.za ; Email: JeenaV1@ukzn.ac.za.
Hoppe HC; Department of Biochemistry and Microbiology , Rhodes University , Grahamstown , 6140 , South Africa.
Jeena V; School of Chemistry and Physics , Pietermaritzburg Campus , University of KwaZulu-Natal , Private Bag X01 , Scottsville , 3209 , South Africa.

RSC Med Chem ; 11(1): 85-91, 2020 Jan 01.

Article en En | MEDLINE | ID: mdl-33479606

Texto completo: 1 Banco de datos: MEDLINE Idioma: En Año: 2020 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Idioma: En Año: 2020 Tipo del documento: Article