Norepinephrine promotes triglyceride storage in macrophages via beta2-adrenergic receptor activation.

Petkevicius, Kasparas; Bidault, Guillaume; Virtue, Sam; Jenkins, Benjamin; van Dierendonck, Xanthe A M H; Dugourd, Aurelien; Saez-Rodriguez, Julio; Stienstra, Rinke; Koulman, Albert; Vidal-Puig, Antonio

Petkevicius, Kasparas; Bidault, Guillaume; Virtue, Sam; Jenkins, Benjamin; van Dierendonck, Xanthe A M H; Dugourd, Aurelien; Saez-Rodriguez, Julio; Stienstra, Rinke; Koulman, Albert; Vidal-Puig, Antonio.

Afiliación

Petkevicius K; Institute of Metabolic Science, MDU MRC, University of Cambridge Metabolic Research Laboratories, Cambridge, United Kingdom.
Bidault G; Institute of Metabolic Science, MDU MRC, University of Cambridge Metabolic Research Laboratories, Cambridge, United Kingdom.
Virtue S; Institute of Metabolic Science, MDU MRC, University of Cambridge Metabolic Research Laboratories, Cambridge, United Kingdom.
Jenkins B; Institute of Metabolic Science, MDU MRC, University of Cambridge Metabolic Research Laboratories, Cambridge, United Kingdom.
van Dierendonck XAMH; Nutrition, Metabolism and Genomics Group, Division of Human Nutrition and Health, Wageningen University, Wageningen, the Netherlands.
Dugourd A; Department of Internal Medicine, Radboud University Medical Center, Nijmegen, the Netherlands.
Saez-Rodriguez J; Joint Research Centre for Computational Biomedicine, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.
Stienstra R; Institute for Computational Biomedicine, Faculty of Medicine & Heidelberg University Hospital, Heidelberg University, Heidelberg, Germany.
Koulman A; Joint Research Centre for Computational Biomedicine, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.
Vidal-Puig A; Institute for Computational Biomedicine, Faculty of Medicine & Heidelberg University Hospital, Heidelberg University, Heidelberg, Germany.

FASEB J ; 35(2): e21266, 2021 02.

Article en En | MEDLINE | ID: mdl-33484195

Asunto(s)

Agonistas Adrenérgicos/farmacología; Macrófagos/metabolismo; Norepinefrina/farmacología; Receptores Adrenérgicos beta 2/metabolismo; Triglicéridos/metabolismo; Animales; Células Cultivadas; Diacilglicerol O-Acetiltransferasa/genética; Diacilglicerol O-Acetiltransferasa/metabolismo; Leucocitos/metabolismo; Gotas Lipídicas/metabolismo; Macrófagos/efectos de los fármacos; Masculino; Ratones; Ratones Endogámicos C57BL; Miocardio/citología; Proteínas de Neoplasias/genética; Proteínas de Neoplasias/metabolismo; Transcriptoma

Palabras clave

adrb2; dgat1; hilpda; immunometabolism; lipid

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Triglicéridos / Norepinefrina / Receptores Adrenérgicos beta 2 / Agonistas Adrenérgicos / Macrófagos Límite: Animals Idioma: En Año: 2021 Tipo del documento: Article

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