Deuterium Depletion Inhibits Cell Proliferation, RNA and Nuclear Membrane Turnover to Enhance Survival in Pancreatic Cancer.

Boros, László G; Somlyai, Ildikó; Kovács, Beáta Zs; Puskás, László G; Nagy, Lajos I; Dux, László; Farkas, Gyula; Somlyai, Gábor

Boros, László G; Somlyai, Ildikó; Kovács, Beáta Zs; Puskás, László G; Nagy, Lajos I; Dux, László; Farkas, Gyula; Somlyai, Gábor.

Afiliación

Boros LG; Department of Pediatrics, Harbor-UCLA Medical Center and The Lundquist Institute for Biomedical Innovation, Torrance, CA, USA.
Somlyai I; SIDMAP, LLC, Los Angeles, CA, USA.
Kovács BZ; HYD LLC for Cancer Research and Drug Development, Budapest, Hungary.
Puskás LG; HYD LLC for Cancer Research and Drug Development, Budapest, Hungary.
Nagy LI; AVIDIN Ltd, Szeged, Hungary.
Dux L; AVIDIN Ltd, Szeged, Hungary.
Farkas G; Department of Biochemistry, Albert Szent-Györgyi Medical University, University of Szeged, Szeged, Hungary.
Somlyai G; Department of Surgery, Albert Szent-Györgyi Medical University, University of Szeged, Szeged, Hungary.

Cancer Control ; 28: 1073274821999655, 2021.

Article en En | MEDLINE | ID: mdl-33760674

Asunto(s)

Deuterio/uso terapéutico; Membrana Nuclear/efectos de los fármacos; Neoplasias Pancreáticas/genética; ARN/efectos de los fármacos; Proliferación Celular; Deuterio/farmacología; Femenino; Humanos; Masculino; Neoplasias Pancreáticas

Palabras clave

NAD(P)H synthesis; deuterium-depleted water (DDW); median survival time (MST); oxidative pentose cycle; peritoneal tumor infiltration; unresectable pancreatic cancer

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Pancreáticas / ARN / Deuterio / Membrana Nuclear Límite: Female / Humans / Male Idioma: En Año: 2021 Tipo del documento: Article

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