Water extract of Er-xian decoction selectively exerts estrogenic activities and interacts with SERMs in estrogen-sensitive tissues.

Wong, Ka-Ying; Zhou, Liping; Yu, Wenxuan; Poon, Christina Chui-Wa; Xiao, Huihui; Chan, Chi-On; Mok, Daniel Kam-Wah; Wong, Man-Sau

Wong, Ka-Ying; Zhou, Liping; Yu, Wenxuan; Poon, Christina Chui-Wa; Xiao, Huihui; Chan, Chi-On; Mok, Daniel Kam-Wah; Wong, Man-Sau.

Afiliación

Wong KY; Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR, PR China.
Zhou L; Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR, PR China; Cell Therapy Center, Xuanwu Hospital Capital Medical University, Beijing, PR China.
Yu W; Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR, PR China.
Poon CC; Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR, PR China.
Xiao H; State Key Laboratory of Chinese Medicine and Molecular Pharmacology (Incubation), The Hong Kong Polytechnic University Shenzhen Research Institute, Shenzhen, 518057, PR China.
Chan CO; Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR, PR China; State Key Laboratory of Chinese Medicine and Molecular Pharmacology (Incubation), The Hong Kong Polytechnic University Shenzhen Research Institute, Shenzhen, 51805
Mok DK; Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR, PR China; State Key Laboratory of Chinese Medicine and Molecular Pharmacology (Incubation), The Hong Kong Polytechnic University Shenzhen Research Institute, Shenzhen, 51805
Wong MS; Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR, PR China; State Key Laboratory of Chinese Medicine and Molecular Pharmacology (Incubation), The Hong Kong Polytechnic University Shenzhen Research Institute, Shenzhen, 51805

J Ethnopharmacol ; 275: 114096, 2021 Jul 15.

Article en En | MEDLINE | ID: mdl-33823166

Asunto(s)

Medicamentos Herbarios Chinos/farmacología; Estrógenos/farmacología; Moduladores Selectivos de los Receptores de Estrógeno/farmacología; Fosfatasa Alcalina/metabolismo; Animales; Peso Corporal/efectos de los fármacos; Huesos/efectos de los fármacos; Huesos/metabolismo; Mama/efectos de los fármacos; Mama/metabolismo; Mama/patología; Línea Celular Tumoral; Sistema Nervioso Central/efectos de los fármacos; Cuerpo Estriado/efectos de los fármacos; Cuerpo Estriado/metabolismo; Medicamentos Herbarios Chinos/química; Medicamentos Herbarios Chinos/uso terapéutico; Estradiol/farmacología; Estradiol/uso terapéutico; Estrógenos/química; Estrógenos/uso terapéutico; Femenino; Interacciones de Hierba-Droga/fisiología; Hormonas/sangre; Humanos; Glándulas Mamarias Humanas/efectos de los fármacos; Medicina Tradicional China; Modelos Biológicos; Ovariectomía/efectos adversos; Clorhidrato de Raloxifeno/farmacología; Clorhidrato de Raloxifeno/uso terapéutico; Ratas Sprague-Dawley; Receptores de Estrógenos/metabolismo; Moduladores Selectivos de los Receptores de Estrógeno/uso terapéutico; Tamoxifeno/farmacología; Tamoxifeno/uso terapéutico; Útero/efectos de los fármacos; Útero/metabolismo; Útero/patología; Agua

Palabras clave

Drug-herb interaction; Er-xian decoction; Estrogen receptor; Postmenopausal osteoporosis; Selective estrogen receptor modulators

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Medicamentos Herbarios Chinos / Moduladores Selectivos de los Receptores de Estrógeno / Estrógenos Tipo de estudio: Diagnostic_studies Idioma: En Año: 2021 Tipo del documento: Article

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