Generation of a tissue-specific transgenic model for K8 phosphomutants: A tool to investigate the role of K8 phosphorylation during skin carcinogenesis in vivo.

Tiwari, Richa; Ganguli, Nirmalya; Alam, Hunain; Sahu, Indrajit; Vadivel, Chella Krishna; Sinha, Shruti; Patel, Shweta; Jamghare, Sayli Nitin; Bane, Sanjay; Thorat, Rahul; Majumdar, Subeer S; Vaidya, Milind M

Tiwari, Richa; Ganguli, Nirmalya; Alam, Hunain; Sahu, Indrajit; Vadivel, Chella Krishna; Sinha, Shruti; Patel, Shweta; Jamghare, Sayli Nitin; Bane, Sanjay; Thorat, Rahul; Majumdar, Subeer S; Vaidya, Milind M.

Afiliación

Tiwari R; Advanced Centre for Treatment Research, and Education in Cancer, Navi Mumbai, India.
Ganguli N; Homi Bhabha National Institute, Mumbai, India.
Alam H; National Institute of Immunology, New Delhi, Delhi, India.
Sahu I; Advanced Centre for Treatment Research, and Education in Cancer, Navi Mumbai, India.
Vadivel CK; Advanced Centre for Treatment Research, and Education in Cancer, Navi Mumbai, India.
Sinha S; Advanced Centre for Treatment Research, and Education in Cancer, Navi Mumbai, India.
Patel S; Advanced Centre for Treatment Research, and Education in Cancer, Navi Mumbai, India.
Jamghare SN; Advanced Centre for Treatment Research, and Education in Cancer, Navi Mumbai, India.
Bane S; Advanced Centre for Treatment Research, and Education in Cancer, Navi Mumbai, India.
Thorat R; Advanced Centre for Treatment Research, and Education in Cancer, Navi Mumbai, India.
Vaidya MM; National Institute of Immunology, New Delhi, Delhi, India.

Cell Biol Int ; 45(8): 1720-1732, 2021 Aug.

Article en En | MEDLINE | ID: mdl-33847415

Asunto(s)

Carcinogénesis/metabolismo; Queratina-8/metabolismo; Mutación/fisiología; Neoplasias Cutáneas/metabolismo; Animales; Carcinogénesis/genética; Carcinogénesis/patología; Electroporación/métodos; Células HEK293; Humanos; Queratina-8/genética; Masculino; Ratones; Ratones Transgénicos; Fosforilación/fisiología; Neoplasias Cutáneas/genética; Neoplasias Cutáneas/patología

Palabras clave

Keratin 14 promoter; Keratin 8 - Serine73 /431 phosphorylation; skin carcinogenesis; transgenic mice

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Cutáneas / Queratina-8 / Carcinogénesis / Mutación Límite: Animals / Humans / Male Idioma: En Año: 2021 Tipo del documento: Article

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