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Analysis of off-target effects in CRISPR-based gene drives in the human malaria mosquito.
Garrood, William T; Kranjc, Nace; Petri, Karl; Kim, Daniel Y; Guo, Jimmy A; Hammond, Andrew M; Morianou, Ioanna; Pattanayak, Vikram; Joung, J Keith; Crisanti, Andrea; Simoni, Alekos.
Afiliación
  • Garrood WT; Department of Life Sciences, Imperial College London, SW7 2AZ London, United Kingdom.
  • Kranjc N; Department of Life Sciences, Imperial College London, SW7 2AZ London, United Kingdom.
  • Petri K; Molecular Pathology Unit, Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA 02129.
  • Kim DY; Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, MA 02129.
  • Guo JA; Molecular Pathology Unit, Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA 02129.
  • Hammond AM; Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, MA 02129.
  • Morianou I; Molecular Pathology Unit, Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA 02129.
  • Pattanayak V; Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, MA 02129.
  • Joung JK; Department of Life Sciences, Imperial College London, SW7 2AZ London, United Kingdom.
  • Crisanti A; W. Harry Feinstone Department of Molecular Microbiology and Immunology, The Johns Hopkins University, Baltimore, MD 21205.
  • Simoni A; Department of Life Sciences, Imperial College London, SW7 2AZ London, United Kingdom.
Proc Natl Acad Sci U S A ; 118(22)2021 06 01.
Article en En | MEDLINE | ID: mdl-34050017

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Genoma de los Insectos / Sistemas CRISPR-Cas / Edición Génica / Mosquitos Vectores / Malaria / Anopheles Tipo de estudio: Risk_factors_studies Límite: Animals / Humans Idioma: En Año: 2021 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Genoma de los Insectos / Sistemas CRISPR-Cas / Edición Génica / Mosquitos Vectores / Malaria / Anopheles Tipo de estudio: Risk_factors_studies Límite: Animals / Humans Idioma: En Año: 2021 Tipo del documento: Article