Ketonuria and Seizure Control in the Medium Chain Triglyceride and Classic Ketogenic Diets.
Can J Neurol Sci
; 49(3): 433-436, 2022 05.
Article
en En
| MEDLINE
| ID: mdl-34075859
ABSTRACT
We hypothesized that children receiving medium-chain triglyceride ketogenic diet (MCTKD) experience similar seizure reduction despite lower ketosis compared with classic ketogenic diet (CKD). Children initiating CKD or MCTKD were enrolled in a prospective observational study. Forty-five children completed 6 months of KD (n = 17 MCTKD, n = 28 CKD). The proportion achieving ≥50% seizure reduction was 71% CKD group and 59% MCTKD group; ≥90% reduction was 32% and 36% in CKD and MCTKD groups, respectively. CKD had higher urine ketones (≥8 mmol/L 79% vs. 36%, p = 0.005). Children receiving MCTKD experience similar seizure control to CKD despite lower urine ketone measures.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Insuficiencia Renal Crónica
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Dieta Cetogénica
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Cetosis
Tipo de estudio:
Observational_studies
Límite:
Child
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Female
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Humans
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Male
Idioma:
En
Año:
2022
Tipo del documento:
Article