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Use of Physiologically Based Pharmacokinetic Modeling for Predicting Drug-Food Interactions: Recommendations for Improving Predictive Performance of Low Confidence Food Effect Models.
Wagner, Christian; Kesisoglou, Filippos; Pepin, Xavier J H; Parrott, Neil; Emami Riedmaier, Arian.
Afiliación
  • Wagner C; Pharmaceutical Technologies, Chemical and Pharmaceutical Development, Merck KGaA, Frankfurter Str. 250, 64293, Darmstadt, Germany. Christian.wagner@merckgroup.com.
  • Kesisoglou F; Pharmaceutical Sciences, Merck & Co., Inc., Kenilworth, New Jersey, USA.
  • Pepin XJH; New Modalities and Parenteral Development, Pharmaceutical Technology & Development, Operations, AstraZeneca, Macclesfield, UK.
  • Parrott N; Pharmaceutical Sciences, Roche Pharmaceutical Research and Early Development, Roche Innovation Center, Basel, Switzerland.
  • Emami Riedmaier A; DMPK and Translational Modeling, AbbVie Inc., North Chicago, Illinois, USA.
AAPS J ; 23(4): 85, 2021 06 17.
Article en En | MEDLINE | ID: mdl-34142242
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Interacciones Alimento-Droga / Modelos Biológicos Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Año: 2021 Tipo del documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Interacciones Alimento-Droga / Modelos Biológicos Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Año: 2021 Tipo del documento: Article