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Phase I study of daily and weekly regimens of the orally administered MDM2 antagonist idasanutlin in patients with advanced tumors.
Italiano, Antoine; Miller, Wilson H; Blay, Jean-Yves; Gietema, Jourik A; Bang, Yung-Jue; Mileshkin, Linda R; Hirte, Hal W; Higgins, Brian; Blotner, Steven; Nichols, Gwen L; Chen, Lin Chi; Petry, Claire; Yang, Qi Joy; Schmitt, Christophe; Jamois, Candice; Siu, Lillian L.
Afiliación
  • Italiano A; Institut Bergonié, Bordeaux, France.
  • Miller WH; Gustave Roussy, Villejuif, France.
  • Blay JY; Faculty of Medicine, University of Bordeaux, Bordeaux, France.
  • Gietema JA; Segal Cancer Centre, Jewish General Hospital, McGill University, Montreal, QC, Canada.
  • Bang YJ; Centre Léon Bérard, Lyon, France.
  • Mileshkin LR; University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
  • Hirte HW; Seoul National University College of Medicine, Seoul, South Korea.
  • Higgins B; Peter MacCallum Cancer Center, Melbourne, Australia.
  • Blotner S; Juravinski Cancer Centre, Hamilton, ON, Canada.
  • Nichols GL; Roche Innovation Center, Hoffmann-La Roche, New York, NY, USA.
  • Chen LC; Roche Innovation Center, Hoffmann-La Roche, New York, NY, USA.
  • Petry C; Roche Innovation Center, Hoffmann-La Roche, New York, NY, USA.
  • Yang QJ; Roche Innovation Center, Hoffmann-La Roche, New York, NY, USA.
  • Schmitt C; Roche Innovation Center, Basel, Switzerland.
  • Jamois C; , Certara, Montréal, QC, Canada.
  • Siu LL; Roche Innovation Center, Basel, Switzerland.
Invest New Drugs ; 39(6): 1587-1597, 2021 12.
Article en En | MEDLINE | ID: mdl-34180037

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Pirrolidinas / Para-Aminobenzoatos / Neoplasias / Antineoplásicos Tipo de estudio: Clinical_trials / Prognostic_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Año: 2021 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Pirrolidinas / Para-Aminobenzoatos / Neoplasias / Antineoplásicos Tipo de estudio: Clinical_trials / Prognostic_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Año: 2021 Tipo del documento: Article