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Castration delays epigenetic aging and feminizes DNA methylation at androgen-regulated loci.
Sugrue, Victoria J; Zoller, Joseph Alan; Narayan, Pritika; Lu, Ake T; Ortega-Recalde, Oscar J; Grant, Matthew J; Bawden, C Simon; Rudiger, Skye R; Haghani, Amin; Bond, Donna M; Hore, Reuben R; Garratt, Michael; Sears, Karen E; Wang, Nan; Yang, Xiangdong William; Snell, Russell G; Hore, Timothy A; Horvath, Steve.
Afiliación
  • Sugrue VJ; Department of Anatomy, University of Otago, Dunedin, New Zealand.
  • Zoller JA; Department of Biostatistics, Fielding School of Public Health, University of California, Los Angeles, Los Angeles, United States.
  • Narayan P; Applied Translational Genetics Group, School of Biological Sciences, Centre for Brain Research, The University of Auckland, Auckland, New Zealand.
  • Lu AT; Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, United States.
  • Ortega-Recalde OJ; Department of Anatomy, University of Otago, Dunedin, New Zealand.
  • Grant MJ; Applied Translational Genetics Group, School of Biological Sciences, Centre for Brain Research, The University of Auckland, Auckland, New Zealand.
  • Bawden CS; Livestock and Farming Systems, South Australian Research and Development Institute, Roseworthy, Australia.
  • Rudiger SR; Livestock and Farming Systems, South Australian Research and Development Institute, Roseworthy, Australia.
  • Haghani A; Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, United States.
  • Bond DM; Department of Anatomy, University of Otago, Dunedin, New Zealand.
  • Hore RR; Blackstone Hill Station, Becks, RD2, Omakau, New Zealand.
  • Garratt M; Department of Anatomy, University of Otago, Dunedin, New Zealand.
  • Sears KE; Department of Ecology and Evolutionary Biology, UCLA, Los Angeles, United States.
  • Wang N; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles (UCLA), Los Angeles, United States.
  • Yang XW; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles (UCLA), Los Angeles, United States.
  • Snell RG; Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine at UCLA, Los Angeles, United States.
  • Hore TA; Applied Translational Genetics Group, School of Biological Sciences, Centre for Brain Research, The University of Auckland, Auckland, New Zealand.
  • Horvath S; Department of Anatomy, University of Otago, Dunedin, New Zealand.
Elife ; 102021 07 06.
Article en En | MEDLINE | ID: mdl-34227937

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Envejecimiento / Orquiectomía / Metilación de ADN / Oveja Doméstica / Epigénesis Genética / Feminización / Andrógenos Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Año: 2021 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Envejecimiento / Orquiectomía / Metilación de ADN / Oveja Doméstica / Epigénesis Genética / Feminización / Andrógenos Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Año: 2021 Tipo del documento: Article