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GIGYF1 loss of function is associated with clonal mosaicism and adverse metabolic health.
Zhao, Yajie; Stankovic, Stasa; Koprulu, Mine; Wheeler, Eleanor; Day, Felix R; Lango Allen, Hana; Kerrison, Nicola D; Pietzner, Maik; Loh, Po-Ru; Wareham, Nicholas J; Langenberg, Claudia; Ong, Ken K; Perry, John R B.
Afiliación
  • Zhao Y; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, UK.
  • Stankovic S; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, UK.
  • Koprulu M; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, UK.
  • Wheeler E; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, UK.
  • Day FR; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, UK.
  • Lango Allen H; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, UK.
  • Kerrison ND; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, UK.
  • Pietzner M; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, UK.
  • Loh PR; Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
  • Wareham NJ; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Langenberg C; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, UK.
  • Ong KK; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, UK.
  • Perry JRB; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, UK.
Nat Commun ; 12(1): 4178, 2021 07 07.
Article en En | MEDLINE | ID: mdl-34234147
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas Portadoras / Predisposición Genética a la Enfermedad / Cromosomas Humanos Y / Diabetes Mellitus Tipo 2 / Mosaicismo Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Año: 2021 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas Portadoras / Predisposición Genética a la Enfermedad / Cromosomas Humanos Y / Diabetes Mellitus Tipo 2 / Mosaicismo Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Año: 2021 Tipo del documento: Article