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Identification of 3,4-Dihydro-2H,6H-pyrimido[1,2-c][1,3]benzothiazin-6-imine Derivatives as Novel Selective Inhibitors of Plasmodium falciparum Dihydroorotate Dehydrogenase.
Hartuti, Endah Dwi; Sakura, Takaya; Tagod, Mohammed S O; Yoshida, Eri; Wang, Xinying; Mochizuki, Kota; Acharjee, Rajib; Matsuo, Yuichi; Tokumasu, Fuyuki; Mori, Mihoko; Waluyo, Danang; Shiomi, Kazuro; Nozaki, Tomoyoshi; Hamano, Shinjiro; Shiba, Tomoo; Kita, Kiyoshi; Inaoka, Daniel Ken.
Afiliación
  • Hartuti ED; Program for Nurturing Global Leaders in Tropical and Emerging Communicable Disease, Graduate School of Biomedical Science, Nagasaki University, Nagasaki 852-8523, Japan.
  • Sakura T; Department of Parasitology, Institute of Tropical Medicine (NEKKEN), Nagasaki University, Nagasaki 852-8523, Japan.
  • Tagod MSO; Laboratory for Biotechnology, Agency for the Assessment and Application of Technology, South Tangerang 15314, Indonesia.
  • Yoshida E; Department of Molecular Infection Dynamics, Institute of Tropical Medicine (NEKKEN), Nagasaki University, Nagasaki 852-8523, Japan.
  • Wang X; School of Tropical Medicine and Global Health, Nagasaki University, Nagasaki 852-8523, Japan.
  • Mochizuki K; School of Tropical Medicine and Global Health, Nagasaki University, Nagasaki 852-8523, Japan.
  • Acharjee R; Department of Molecular Infection Dynamics, Institute of Tropical Medicine (NEKKEN), Nagasaki University, Nagasaki 852-8523, Japan.
  • Matsuo Y; School of Tropical Medicine and Global Health, Nagasaki University, Nagasaki 852-8523, Japan.
  • Tokumasu F; Department of Biomedical Chemistry, Graduate School of Medicine, The University of Tokyo, Tokyo 113-0033, Japan.
  • Mori M; Department of Immunogenetics, Institute of Tropical Medicine (NEKKEN), Nagasaki University, Nagasaki 852-8523, Japan.
  • Waluyo D; Program for Nurturing Global Leaders in Tropical and Emerging Communicable Disease, Graduate School of Biomedical Science, Nagasaki University, Nagasaki 852-8523, Japan.
  • Shiomi K; Department of Parasitology, Institute of Tropical Medicine (NEKKEN), Nagasaki University, Nagasaki 852-8523, Japan.
  • Nozaki T; Departement of Zoology, University of Chittagong, Chittagong 4331, Bangladesh.
  • Hamano S; School of Tropical Medicine and Global Health, Nagasaki University, Nagasaki 852-8523, Japan.
  • Shiba T; Graduate School of Life Science, Kumamoto University, Kumamoto 860-0862, Japan.
  • Kita K; Department of Cellular Architecture Studies, Institute of Tropical Medicine (NEKKEN), Nagasaki University, Nagasaki 852-8523, Japan.
  • Inaoka DK; Biological Resource Center, NITE, Kisarazu, Chiba 292-0818, Japan.
Int J Mol Sci ; 22(13)2021 Jul 05.
Article en En | MEDLINE | ID: mdl-34281290
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Plasmodium falciparum / Pirimidinas / Proteínas Protozoarias / Oxidorreductasas actuantes sobre Donantes de Grupo CH-CH / Inhibidores Enzimáticos / Iminas / Antimaláricos Tipo de estudio: Diagnostic_studies Límite: Animals / Humans Idioma: En Año: 2021 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Plasmodium falciparum / Pirimidinas / Proteínas Protozoarias / Oxidorreductasas actuantes sobre Donantes de Grupo CH-CH / Inhibidores Enzimáticos / Iminas / Antimaláricos Tipo de estudio: Diagnostic_studies Límite: Animals / Humans Idioma: En Año: 2021 Tipo del documento: Article