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Discovery and characterization of novel peptide inhibitors of the NRF2/MAFG/DNA ternary complex for the treatment of cancer.
Simov, Vladimir; Altman, Michael D; Bianchi, Elisabetta; DelRizzo, Sonia; DiNunzio, Edward N; Feng, Guo; Goldenblatt, Peter; Ingenito, Raffaele; Johnson, Scott A; Mansueto, My Sam; Mayhood, Todd; Mortison, Jonathan D; Serebrov, Victor; Sondey, Christopher; Sriraman, Venkat; Tucker, Thomas J; Walji, Abbas; Wan, Hui; Yue, Yingzi; Stoeck, Alexander; DiMauro, Erin F.
Afiliación
  • Simov V; Merck & Co., Inc., Chemistry, 33 Avenue Louis Pasteur, Boston, MA 02127, USA. Electronic address: vladimir_simov@merck.com.
  • Altman MD; Merck & Co., Inc., Chemistry, 33 Avenue Louis Pasteur, Boston, MA 02127, USA.
  • Bianchi E; Peptides and Small Molecules R&D, IRBM, Via Pontina, 30,600, 00071 Pomezia RM, Italy.
  • DelRizzo S; Peptides and Small Molecules R&D, IRBM, Via Pontina, 30,600, 00071 Pomezia RM, Italy.
  • DiNunzio EN; Merck & Co., Inc., Chemistry, 2000 Galloping Hill Road, K-15, Kenilworth, NJ 07033, USA.
  • Feng G; Merck & Co., Inc., Quantitative Biosciences, 33 Avenue Louis Pasteur, Boston, MA 02127, USA.
  • Goldenblatt P; Merck & Co., Inc., Quantitative Biosciences, 33 Avenue Louis Pasteur, Boston, MA 02127, USA.
  • Ingenito R; Peptides and Small Molecules R&D, IRBM, Via Pontina, 30,600, 00071 Pomezia RM, Italy.
  • Johnson SA; Merck & Co., Inc., Chemistry, 33 Avenue Louis Pasteur, Boston, MA 02127, USA.
  • Mansueto MS; Merck & Co., Inc., Quantitative Biosciences, 33 Avenue Louis Pasteur, Boston, MA 02127, USA.
  • Mayhood T; Merck & Co., Inc., Chemistry, 2000 Galloping Hill Road, K-15, Kenilworth, NJ 07033, USA.
  • Mortison JD; Merck & Co., Inc., Chemistry, 33 Avenue Louis Pasteur, Boston, MA 02127, USA.
  • Serebrov V; Merck & Co., Inc., Quantitative Biosciences, 33 Avenue Louis Pasteur, Boston, MA 02127, USA.
  • Sondey C; Merck & Co., Inc., Quantitative Biosciences, 33 Avenue Louis Pasteur, Boston, MA 02127, USA.
  • Sriraman V; Merck & Co., Inc., Quantitative Biosciences, 33 Avenue Louis Pasteur, Boston, MA 02127, USA.
  • Tucker TJ; Merck & Co., Inc., Chemistry, 770 Sumneytown Pike, West Point, PA 19486, USA.
  • Walji A; Merck & Co., Inc., Chemistry, 770 Sumneytown Pike, West Point, PA 19486, USA.
  • Wan H; Merck & Co., Inc., PPDM, 126 East Lincoln Avenue, Rahway, NJ 07065, USA.
  • Yue Y; Merck & Co., Inc., Biology, 33 Avenue Louis Pasteur, Boston, MA 02127, USA.
  • Stoeck A; Merck & Co., Inc., Biology, 33 Avenue Louis Pasteur, Boston, MA 02127, USA.
  • DiMauro EF; Merck & Co., Inc., Chemistry, 33 Avenue Louis Pasteur, Boston, MA 02127, USA.
Eur J Med Chem ; 224: 113686, 2021 Nov 15.
Article en En | MEDLINE | ID: mdl-34303079
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Péptidos / ADN / Factor de Transcripción MafG / Factor 2 Relacionado con NF-E2 Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Año: 2021 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Péptidos / ADN / Factor de Transcripción MafG / Factor 2 Relacionado con NF-E2 Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Año: 2021 Tipo del documento: Article