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Helicase primase inhibitors (HPIs) are efficacious for therapy of human herpes simplex virus (HSV) disease in an infection mouse model.
Uhlig, Nadja; Donner, Anne-Kathrin; Gege, Christian; Lange, Franziska; Kleymann, Gerald; Grunwald, Thomas.
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  • Uhlig N; Fraunhofer-Institute for Cell Therapy and Immunology IZI, Division Vaccines and Infection Models, Unit Preclinical Validation, Perlickstrasse 1, 04103, Leipzig, Germany.
  • Donner AK; Fraunhofer-Institute for Cell Therapy and Immunology IZI, Division Vaccines and Infection Models, Unit Preclinical Validation, Perlickstrasse 1, 04103, Leipzig, Germany.
  • Gege C; Innovative Molecules GmbH, Leopoldshöher Str. 7, 32107, Bad Salzuflen, Germany.
  • Lange F; Fraunhofer-Institute for Cell Therapy and Immunology IZI, Center for Experimental Medicine, Perlickstrasse 1, 04103, Leipzig, Germany.
  • Kleymann G; Innovative Molecules GmbH, Leopoldshöher Str. 7, 32107, Bad Salzuflen, Germany; University of Tübingen, Interfaculty Institute of Biochemistry, Auf der Morgenstelle 34, 72076, Tübingen, Germany.
  • Grunwald T; Fraunhofer-Institute for Cell Therapy and Immunology IZI, Division Vaccines and Infection Models, Unit Preclinical Validation, Perlickstrasse 1, 04103, Leipzig, Germany. Electronic address: thomas.grunwald@izi.fraunhofer.de.
Antiviral Res ; 195: 105190, 2021 11.
Article en En | MEDLINE | ID: mdl-34666109
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Antivirales / Herpesvirus Humano 1 / ADN Helicasas / ADN Primasa / Herpes Simple Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Año: 2021 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Antivirales / Herpesvirus Humano 1 / ADN Helicasas / ADN Primasa / Herpes Simple Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Año: 2021 Tipo del documento: Article