SARS-CoV-2 and lung injury: Dysregulation of immune response but not hyperimmune response as in "cytokine storm syndrome".
Clin Respir J
; 16(1): 13-16, 2022 Jan.
Article
en En
| MEDLINE
| ID: mdl-34674363
ABSTRACT
SARS-CoV-2 infection can present either an asymptomatic or symptomatic; the spectrum of symptomatic infection ranges from mild to critical. A majority of patients have experienced mild symptoms with a good prognosis. But approximately 14% of them have severe infection presenting with hypoxemia and extensive lung involvement. The current mini-review describes the dysregulation of immune response for SARS-CoV-2 viral pneumonia and virus-induced lung injury. Also, many confounding factors can increase lung injury, in addition to virus-induced lung injury. Especially in critically ill patients, confounding factors can cause the inflammatory cascade, acute respiratory distress syndrome (ARDS), and mortality.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Lesión Pulmonar Aguda
/
COVID-19
Tipo de estudio:
Prognostic_studies
Límite:
Humans
Idioma:
En
Año:
2022
Tipo del documento:
Article