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Rat Blood Leukocytes after Intravenous Injection of Magnetoliposomes on the Basis of Nanomagnetite.
Mil'to, I V; Ivanova, V V; Shevtsova, N M; Serebryakova, O N; Ivanov, A A; Gereng, E A; Takhauov, R M; Sukhodolo, I V.
Afiliación
  • Mil'to IV; Department of Morphology and General Pathology, Siberian State Medical University, Ministry of Health of the Russian Federation, Tomsk, Russia. milto_bio@mail.ru.
  • Ivanova VV; Department of Molecular and Cellular Radiology, Seversk Biophysical Research Center, Federal Medical-Biological Agency, Seversk, Russia. milto_bio@mail.ru.
  • Shevtsova NM; Department of Morphology and General Pathology, Siberian State Medical University, Ministry of Health of the Russian Federation, Tomsk, Russia.
  • Serebryakova ON; Department of Morphology and General Pathology, Siberian State Medical University, Ministry of Health of the Russian Federation, Tomsk, Russia.
  • Ivanov AA; Department of Morphology and General Pathology, Siberian State Medical University, Ministry of Health of the Russian Federation, Tomsk, Russia.
  • Gereng EA; Common Use Center "Physico-Сhemical Analysis Methods", National Research Tomsk Polytechnic University, Tomsk, Russia.
  • Takhauov RM; Department of Morphology and General Pathology, Siberian State Medical University, Ministry of Health of the Russian Federation, Tomsk, Russia.
  • Sukhodolo IV; Department of Molecular and Cellular Radiology, Seversk Biophysical Research Center, Federal Medical-Biological Agency, Seversk, Russia.
Bull Exp Biol Med ; 171(6): 774-777, 2021 Oct.
Article en En | MEDLINE | ID: mdl-34705182
ABSTRACT
The structure of blood neutrophils, eosinophils, monocytes, and lymphocytes and differential white blood count in adult rats were studied over 120 days after a single intravenous injection of magnetoliposomes based on nanomagnetite. Magnetoliposomes had no effect on the structure of neutrophils, eosinophils, monocytes, and lymphocytes. At the same time, injection of a suspension of magnetoliposomes based on magnetite nanoparticles led to a decrease in lymphocyte count and an increase in the count of monocytes and band and segmented neutrophils in the blood. These changes were transient and the parameters returned to normal by day 40-60 after injection.
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Linfocitos / Monocitos / Eosinófilos / Nanopartículas de Magnetita / Liposomas / Neutrófilos Límite: Animals Idioma: En Año: 2021 Tipo del documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Linfocitos / Monocitos / Eosinófilos / Nanopartículas de Magnetita / Liposomas / Neutrófilos Límite: Animals Idioma: En Año: 2021 Tipo del documento: Article