Investigating immunological interaction between lymphatic filariasis and COVID-19 infection: a preliminary evidence.
Hum Vaccin Immunother
; 17(12): 5150-5152, 2021 Dec 02.
Article
en En
| MEDLINE
| ID: mdl-34715006
ABSTRACT
The foremost concerns of COVID-19 vaccines are safety and efficacy, which becomes grave in countries with a high burden of Neglected Tropical Diseases. Studies proposed helminthic infections might alleviate the efficacy of COVID-19 vaccines. We share preliminary evidence on the association between filariasis and COVID-19 infection. We collated 2 ml of blood from 174 participants residing in filariasis endemic area. To determine filarial antigen, the Og4C3 test and for COVID-19 antibodies, tests through ELISA was performed. COVID-19 antibodies were present among 74/174 (42.5%), whereas filarial antigens were detected in 24/174 (13.8%) participants. An insignificant association [OR = 0.855 (0.36-2.034)] between two was observed. Hence, people in filarial endemic regions can continue taking vaccines without worrying about their efficacy due to the helminthic load in community.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Filariasis Linfática
/
COVID-19
Límite:
Animals
/
Humans
Idioma:
En
Año:
2021
Tipo del documento:
Article