Paeonol reduces IL-ß production by inhibiting the activation of nucleotide oligomerization domain-like receptor protein-3 inflammasome and nuclear factor-&#954;B in macrophages.

Chen, Gang; Guo, Tingwang; Yang, Lin

Paeonol reduces IL-ß production by inhibiting the activation of nucleotide oligomerization domain-like receptor protein-3 inflammasome and nuclear factor-κB in macrophages.

Chen, Gang; Guo, Tingwang; Yang, Lin.

Afiliación

Chen G; Key Laboratory of Natural Medicine Research of Chongqing Education Commission, College of Environment and Resources, Chongqing Technology and Business University, Chongqing 400067, China.
Guo T; Key Laboratory of Natural Medicine Research of Chongqing Education Commission, College of Environment and Resources, Chongqing Technology and Business University, Chongqing 400067, China.
Yang L; Key Laboratory of Natural Medicine Research of Chongqing Education Commission, College of Environment and Resources, Chongqing Technology and Business University, Chongqing 400067, China.

Biochem Cell Biol ; 100(1): 28-36, 2022 02.

Article en En | MEDLINE | ID: mdl-34784237

Asunto(s)

Inflamasomas; FN-kappa B; Acetofenonas; Animales; Proteínas Portadoras/metabolismo; Caspasa 1/metabolismo; Caspasa 1/farmacología; Inflamasomas/metabolismo; Inflamasomas/farmacología; Inflamación/metabolismo; Lipopolisacáridos/farmacología; Macrófagos; Inhibidor NF-kappaB alfa/metabolismo; FN-kappa B/metabolismo; Proteína con Dominio Pirina 3 de la Familia NLR/metabolismo; Nucleótidos/metabolismo; Nucleótidos/farmacología; Ratas; Ácido Úrico/metabolismo; Ácido Úrico/farmacología

Palabras clave

IL-1ß; NF-κB; NLRP3 inflammasome; gout; goutte; paeonol; paéonol

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: FN-kappa B / Inflamasomas Límite: Animals Idioma: En Año: 2022 Tipo del documento: Article

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: FN-kappa B / Inflamasomas Límite: Animals Idioma: En Año: 2022 Tipo del documento: Article