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Preclinical and randomized phase I studies of plitidepsin in adults hospitalized with COVID-19.
Varona, Jose F; Landete, Pedro; Lopez-Martin, Jose A; Estrada, Vicente; Paredes, Roger; Guisado-Vasco, Pablo; Fernandez de Orueta, Lucia; Torralba, Miguel; Fortun, Jesus; Vates, Roberto; Barberan, Jose; Clotet, Bonaventura; Ancochea, Julio; Carnevali, Daniel; Cabello, Noemi; Porras, Lourdes; Gijon, Paloma; Monereo, Alfonso; Abad, Daniel; Zuñiga, Sonia; Sola, Isabel; Rodon, Jordi; Vergara-Alert, Julia; Izquierdo-Useros, Nuria; Fudio, Salvador; Pontes, Maria Jose; de Rivas, Beatriz; Giron de Velasco, Patricia; Nieto, Antonio; Gomez, Javier; Aviles, Pablo; Lubomirov, Rubin; Belgrano, Alvaro; Sopesen, Belen; White, Kris M; Rosales, Romel; Yildiz, Soner; Reuschl, Ann-Kathrin; Thorne, Lucy G; Jolly, Clare; Towers, Greg J; Zuliani-Alvarez, Lorena; Bouhaddou, Mehdi; Obernier, Kirsten; McGovern, Briana L; Rodriguez, M Luis; Enjuanes, Luis; Fernandez-Sousa, Jose M; Krogan, Nevan J; Jimeno, Jose M.
Afiliación
  • Varona JF; Departamento de Medicina Interna, Hospital Universitario HM Monteprincipe, HM Hospitales, Madrid, Spain jfvarona@hmhospitales.com.
  • Landete P; Facultad de Medicina, Universidad San Pablo-CEU, Madrid, Spain.
  • Lopez-Martin JA; Hospital Universitario La Princesa, Madrid, Spain.
  • Estrada V; Universidad Autónoma de Madrid, Madrid, Spain.
  • Paredes R; Virology and Inflammation Unit, PharmaMar, SA, Madrid, Spain.
  • Guisado-Vasco P; Hospital Clínico San Carlos, Madrid, Spain.
  • Fernandez de Orueta L; Universidad Complutense de Madrid, Madrid, Spain.
  • Torralba M; Infectious Diseases Department, IrsiCaixa AIDS Research Institute, Barcelona, Spain.
  • Fortun J; Hospital Germans Trias I Pujol, Barcelona, Spain.
  • Vates R; Hospital Universitario Quironsalud Madrid, Madrid, Spain.
  • Barberan J; Universidad Europea, Madrid, Spain.
  • Clotet B; Universidad Europea, Madrid, Spain.
  • Ancochea J; Internal Medicine Department, Hospital Universitario de Getafe, Madrid, Spain.
  • Carnevali D; Health Sciences Faculty, University of Alcalá, Madrid, Spain.
  • Cabello N; Guadalajara University Hospital, Guadalajara, Spain.
  • Porras L; Hospital Universitario Ramón y Cajal, Madrid, Spain.
  • Gijon P; Internal Medicine Department, Hospital Universitario de Getafe, Madrid, Spain.
  • Monereo A; Departamento de Medicina Interna, Hospital Universitario HM Monteprincipe, HM Hospitales, Madrid, Spain.
  • Abad D; Facultad de Medicina, Universidad San Pablo-CEU, Madrid, Spain.
  • Zuñiga S; Infectious Diseases Department, IrsiCaixa AIDS Research Institute, Barcelona, Spain.
  • Sola I; Hospital Germans Trias I Pujol, Barcelona, Spain.
  • Rodon J; Universitat Autònoma de Barcelona, Barcelona, Spain.
  • Vergara-Alert J; Universitat de Vic, Universitat Central de Catalunya, Barcelona, Spain.
  • Izquierdo-Useros N; Hospital Universitario La Princesa, Madrid, Spain.
  • Fudio S; Universidad Autónoma de Madrid, Madrid, Spain.
  • Pontes MJ; Centro de Investigación en Red de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III (ISCIII), Madrid, Spain.
  • de Rivas B; Hospital Universitario Quironsalud Madrid, Madrid, Spain.
  • Giron de Velasco P; Universidad Europea, Madrid, Spain.
  • Nieto A; Infectious Diseases Department, Clinico San Carlos University Hospital, Madrid, Spain.
  • Gomez J; Internal Medicine, Hospital General de Ciudad Real, Ciudad Real, Spain.
  • Aviles P; Clinical Microbiology and Infectious Diseases Department, Hospital General Universitario Gregorio Marañón, Instituto de Investigación Sanitaria Gregorio Marañón, Madrid, Spain.
  • Lubomirov R; Internal Medicine Department, Hospital Universitario de Getafe, Madrid, Spain.
  • Belgrano A; Universidad Europea, Madrid, Spain.
  • Sopesen B; Internal Medicine Department, Hospital Universitario de Getafe, Madrid, Spain.
  • White KM; Department of Molecular and Cell Biology, Centro Nacional de Biotecnología (CNB-CSIC), Madrid, Spain.
  • Rosales R; Department of Molecular and Cell Biology, Centro Nacional de Biotecnología (CNB-CSIC), Madrid, Spain.
  • Yildiz S; IRTA, Centre de Recerca en Sanitat Animal (CReSA, IRTA-UAB), Campus de la UAB, Bellaterra, Spain.
  • Reuschl AK; IRTA, Centre de Recerca en Sanitat Animal (CReSA, IRTA-UAB), Campus de la UAB, Bellaterra, Spain.
  • Thorne LG; IrsiCaixa AIDS Research Institute, Barcelona, Spain.
  • Jolly C; Germans Trias I Pujol Research Institute (IGTP), Badalona, Spain.
  • Towers GJ; Clinical Pharmacology Unit, PharmaMar, Madrid, Spain.
  • Zuliani-Alvarez L; Medical Affairs, PharmaMar, Madrid, Spain.
  • Bouhaddou M; Medical Affairs, PharmaMar, Madrid, Spain.
  • Obernier K; Virology and Inflammation Unit, PharmaMar, SA, Madrid, Spain.
  • McGovern BL; Bio Statistics Unit, PharmaMar, Madrid, Spain.
  • Rodriguez ML; Bio Statistics Unit, PharmaMar, Madrid, Spain.
  • Enjuanes L; Preclinical Unit, Pharmamar, Madrid, Spain.
  • Fernandez-Sousa JM; Clinical Pharmacology Unit, PharmaMar, Madrid, Spain.
  • Krogan NJ; Bio Statistics Unit, PharmaMar, Madrid, Spain.
  • Jimeno JM; Virology and Inflammation Unit, PharmaMar, SA, Madrid, Spain.
Life Sci Alliance ; 5(4)2022 04.
Article en En | MEDLINE | ID: mdl-35012962
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Péptidos Cíclicos / Depsipéptidos / SARS-CoV-2 / Tratamiento Farmacológico de COVID-19 / Hospitalización Tipo de estudio: Clinical_trials Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Año: 2022 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Péptidos Cíclicos / Depsipéptidos / SARS-CoV-2 / Tratamiento Farmacológico de COVID-19 / Hospitalización Tipo de estudio: Clinical_trials Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Año: 2022 Tipo del documento: Article