Inhibition of SARS-CoV-2 infection in human iPSC-derived cardiomyocytes by targeting the Sigma-1 receptor disrupts cytoarchitecture and beating.

Salerno, José Alexandre; Torquato, Thayana; Temerozo, Jairo R; Goto-Silva, Livia; Karmirian, Karina; Mendes, Mayara A; Sacramento, Carolina Q; Fintelman-Rodrigues, Natalia; Souza, Letícia R Q; Ornelas, Isis M; Veríssimo, Carla P; Aragão, Luiz Guilherme H S; Vitória, Gabriela; Pedrosa, Carolina S G; da Silva Gomes Dias, Suelen; Cardoso Soares, Vinicius; Puig-Pijuan, Teresa; Salazar, Vinícius; Dariolli, Rafael; Biagi, Diogo; Furtado, Daniel R; Barreto Chiarini, Luciana; Borges, Helena L; Bozza, Patrícia T; Zaluar P Guimarães, Marilia; Souza, Thiago M L; Rehen, Stevens K

Salerno, José Alexandre; Torquato, Thayana; Temerozo, Jairo R; Goto-Silva, Livia; Karmirian, Karina; Mendes, Mayara A; Sacramento, Carolina Q; Fintelman-Rodrigues, Natalia; Souza, Letícia R Q; Ornelas, Isis M; Veríssimo, Carla P; Aragão, Luiz Guilherme H S; Vitória, Gabriela; Pedrosa, Carolina S G; da Silva Gomes Dias, Suelen; Cardoso Soares, Vinicius; Puig-Pijuan, Teresa; Salazar, Vinícius; Dariolli, Rafael; Biagi, Diogo; Furtado, Daniel R; Barreto Chiarini, Luciana; Borges, Helena L; Bozza, Patrícia T; Zaluar P Guimarães, Marilia; Souza, Thiago M L; Rehen, Stevens K.

Afiliación

Salerno JA; Institute of Biomedical Sciences, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, Brazil.
Torquato T; D'Or Institute for Research and Education (IDOR), Rio de Janeiro, Brazil.
Temerozo JR; D'Or Institute for Research and Education (IDOR), Rio de Janeiro, Brazil.
Goto-Silva L; National Institute for Science and Technology on Neuroimmunomodulation (INCT/NIM), Oswaldo Cruz Institute (IOC), Oswaldo Cruz Foundation (Fiocruz), Rio de Janeiro, Brazil.
Karmirian K; Laboratory on Thymus Research, Oswaldo Cruz Institute (IOC), Oswaldo Cruz Foundation (Fiocruz), Rio de Janeiro, Brazil.
Mendes MA; D'Or Institute for Research and Education (IDOR), Rio de Janeiro, Brazil.
Sacramento CQ; Institute of Biomedical Sciences, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, Brazil.
Fintelman-Rodrigues N; D'Or Institute for Research and Education (IDOR), Rio de Janeiro, Brazil.
Souza LRQ; D'Or Institute for Research and Education (IDOR), Rio de Janeiro, Brazil.
Ornelas IM; Immunopharmacology Laboratory, Oswaldo Cruz Institute (IOC), Oswaldo Cruz Foundation (Fiocruz), Rio de Janeiro, Brazil.
Veríssimo CP; National Institute for Science and Technology on Innovation in Diseases of Neglected Populations (INCT/IDPN), Center for Technological Development in Health (CDTS), Oswaldo Cruz Foundation (Fiocruz), Rio de Janeiro, Brazil.
Aragão LGHS; Immunopharmacology Laboratory, Oswaldo Cruz Institute (IOC), Oswaldo Cruz Foundation (Fiocruz), Rio de Janeiro, Brazil.
Vitória G; National Institute for Science and Technology on Innovation in Diseases of Neglected Populations (INCT/IDPN), Center for Technological Development in Health (CDTS), Oswaldo Cruz Foundation (Fiocruz), Rio de Janeiro, Brazil.
Pedrosa CSG; D'Or Institute for Research and Education (IDOR), Rio de Janeiro, Brazil.
da Silva Gomes Dias S; D'Or Institute for Research and Education (IDOR), Rio de Janeiro, Brazil.
Cardoso Soares V; Institute of Biomedical Sciences, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, Brazil.
Puig-Pijuan T; D'Or Institute for Research and Education (IDOR), Rio de Janeiro, Brazil.
Salazar V; D'Or Institute for Research and Education (IDOR), Rio de Janeiro, Brazil.
Dariolli R; D'Or Institute for Research and Education (IDOR), Rio de Janeiro, Brazil.
Biagi D; Immunopharmacology Laboratory, Oswaldo Cruz Institute (IOC), Oswaldo Cruz Foundation (Fiocruz), Rio de Janeiro, Brazil.
Furtado DR; Institute of Biomedical Sciences, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, Brazil.
Barreto Chiarini L; Immunopharmacology Laboratory, Oswaldo Cruz Institute (IOC), Oswaldo Cruz Foundation (Fiocruz), Rio de Janeiro, Brazil.
Borges HL; D'Or Institute for Research and Education (IDOR), Rio de Janeiro, Brazil.
Bozza PT; Carlos Chagas Filho Institute of Biophysics (IBCCF), Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, Brazil.
Zaluar P Guimarães M; Department of Systems and Computer Engineering, COPPE, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, Brazil.
Souza TML; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, United States of America.
Rehen SK; PluriCell Biotech, São Paulo, Brazil.