Stem bark of <i>Fraxinus rhynchophylla</i> ameliorates the severity of pancreatic fibrosis by regulating the TGF-ß/Smad signaling pathway.

Choi, Ji-Won; Shin, Joon Yeon; Zhou, Ziqi; Kim, Dong-Uk; Kweon, Bitna; Oh, Hyuncheol; Kim, Youn-Chul; Song, Ho-Joon; Bae, Gi-Sang; Park, Sung-Joo

Stem bark of Fraxinus rhynchophylla ameliorates the severity of pancreatic fibrosis by regulating the TGF-ß/Smad signaling pathway.

Choi, Ji-Won; Shin, Joon Yeon; Zhou, Ziqi; Kim, Dong-Uk; Kweon, Bitna; Oh, Hyuncheol; Kim, Youn-Chul; Song, Ho-Joon; Bae, Gi-Sang; Park, Sung-Joo.

Afiliación

Choi JW; Department of Herbology, School of Korean Medicine, Wonkwang University, Iksan, Jeollabuk-do, Republic of Korea.
Shin JY; Hanbang Cardio-Renal Syndrome Research Center, School of Korean Medicine, Wonkwang University, Iksan, Jeollabuk-do, Republic of Korea.
Zhou Z; Department of Herbology, School of Korean Medicine, Wonkwang University, Iksan, Jeollabuk-do, Republic of Korea.
Kim DU; Department of Herbology, School of Korean Medicine, Wonkwang University, Iksan, Jeollabuk-do, Republic of Korea.
Kweon B; Hanbang Cardio-Renal Syndrome Research Center, School of Korean Medicine, Wonkwang University, Iksan, Jeollabuk-do, Republic of Korea.
Oh H; Department of Herbology, School of Korean Medicine, Wonkwang University, Iksan, Jeollabuk-do, Republic of Korea.
Kim YC; Institute of Pharmaceutical Research and Development, College of Pharmacy, WonkwangUniversity, Iksan, Jeollabuk-do, Republic of Korea.
Song HJ; Institute of Pharmaceutical Research and Development, College of Pharmacy, WonkwangUniversity, Iksan, Jeollabuk-do, Republic of Korea.
Bae GS; Department of Herbology, School of Korean Medicine, Wonkwang University, Iksan, Jeollabuk-do, Republic of Korea.
Park SJ; Hanbang Cardio-Renal Syndrome Research Center, School of Korean Medicine, Wonkwang University, Iksan, Jeollabuk-do, Republic of Korea parksj08@wku.ac.kr baegs888@wku.ac.kr.

J Investig Med ; 70(5): 1285-1292, 2022 06.

Article en En | MEDLINE | ID: mdl-35078865

Asunto(s)

Fraxinus; Pancreatitis Crónica; Animales; Ceruletida/metabolismo; Ceruletida/farmacología; Ceruletida/uso terapéutico; Colágeno/metabolismo; Colágeno/farmacología; Colágeno/uso terapéutico; Fibrosis; Humanos; Ratones; Páncreas/patología; Pancreatitis Crónica/tratamiento farmacológico; Pancreatitis Crónica/metabolismo; Pancreatitis Crónica/patología; Corteza de la Planta/metabolismo; Transducción de Señal; Factor de Crecimiento Transformador beta/metabolismo

Palabras clave

fibroblasts; pancreatitis; transforming growth factors

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Fraxinus / Pancreatitis Crónica Límite: Animals / Humans Idioma: En Año: 2022 Tipo del documento: Article

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Fraxinus / Pancreatitis Crónica Límite: Animals / Humans Idioma: En Año: 2022 Tipo del documento: Article