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Signatures of TOP1 transcription-associated mutagenesis in cancer and germline.
Reijns, Martin A M; Parry, David A; Williams, Thomas C; Nadeu, Ferran; Hindshaw, Rebecca L; Rios Szwed, Diana O; Nicholson, Michael D; Carroll, Paula; Boyle, Shelagh; Royo, Romina; Cornish, Alex J; Xiang, Hang; Ridout, Kate; Schuh, Anna; Aden, Konrad; Palles, Claire; Campo, Elias; Stankovic, Tatjana; Taylor, Martin S; Jackson, Andrew P.
Afiliación
  • Reijns MAM; Disease Mechanisms, MRC Human Genetics Unit, Institute of Genetics and Cancer, The University of Edinburgh, Edinburgh, UK. martin.reijns@ed.ac.uk.
  • Parry DA; Disease Mechanisms, MRC Human Genetics Unit, Institute of Genetics and Cancer, The University of Edinburgh, Edinburgh, UK.
  • Williams TC; Disease Mechanisms, MRC Human Genetics Unit, Institute of Genetics and Cancer, The University of Edinburgh, Edinburgh, UK.
  • Nadeu F; Biomedical Genomics, MRC Human Genetics Unit, Institute of Genetics and Cancer, The University of Edinburgh, Edinburgh, UK.
  • Hindshaw RL; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.
  • Rios Szwed DO; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain.
  • Nicholson MD; Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, UK.
  • Carroll P; Disease Mechanisms, MRC Human Genetics Unit, Institute of Genetics and Cancer, The University of Edinburgh, Edinburgh, UK.
  • Boyle S; Cancer Research UK Edinburgh Centre, Institute of Genetics and Cancer, The University of Edinburgh, Edinburgh, UK.
  • Royo R; Disease Mechanisms, MRC Human Genetics Unit, Institute of Genetics and Cancer, The University of Edinburgh, Edinburgh, UK.
  • Cornish AJ; Genome Regulation, MRC Human Genetics Unit, Institute of Genetics and Cancer, The University of Edinburgh, Edinburgh, UK.
  • Xiang H; Barcelona Supercomputing Center (BSC), Barcelona, Spain.
  • Ridout K; The Institute of Cancer Research, London, UK.
  • Palles C; Department of Oncology, University of Oxford, Oxford, UK.
  • Campo E; Institute of Clinical Molecular Biology, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Kiel, Germany.
  • Stankovic T; Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, UK.
  • Taylor MS; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.
  • Jackson AP; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain.
Nature ; 602(7898): 623-631, 2022 02.
Article en En | MEDLINE | ID: mdl-35140396
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Mutagénesis / ADN-Topoisomerasas de Tipo I / Células Germinativas / Neoplasias Tipo de estudio: Risk_factors_studies Límite: Animals / Humans Idioma: En Año: 2022 Tipo del documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Mutagénesis / ADN-Topoisomerasas de Tipo I / Células Germinativas / Neoplasias Tipo de estudio: Risk_factors_studies Límite: Animals / Humans Idioma: En Año: 2022 Tipo del documento: Article