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Rational design of small-molecules to recognize G-quadruplexes of c-MYC promoter and telomere and the evaluation of their in vivo antitumor activity against breast cancer.
Long, Wei; Zheng, Bo-Xin; Li, Ying; Huang, Xuan-He; Lin, Dan-Min; Chen, Cui-Cui; Hou, Jin-Qiang; Ou, Tian-Miao; Wong, Wing-Leung; Zhang, Kun; Lu, Yu-Jing.
Afiliación
  • Long W; School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou 510006, PR China.
  • Zheng BX; School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou 510006, PR China.
  • Li Y; School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou 510006, PR China.
  • Huang XH; School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou 510006, PR China.
  • Lin DM; School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou 510006, PR China.
  • Chen CC; School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou 510006, PR China.
  • Hou JQ; Department of Chemistry, Lakehead University, 955 Oliver Road, Thunder Bay, Ontario P7B 5E1, Canada.
  • Ou TM; Thunder Bay Regional Health Research Institute, 980 Oliver Road, Thunder Bay, Ontario P7B 6V4, Canada.
  • Wong WL; Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, China.
  • Zhang K; State Key Laboratory of Chemical Biology and Drug Discovery, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Hong Kong SAR, China.
  • Lu YJ; School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou 510006, PR China.
Nucleic Acids Res ; 50(4): 1829-1848, 2022 02 28.
Article en En | MEDLINE | ID: mdl-35166828
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias de la Mama / G-Cuádruplex / Antineoplásicos Límite: Animals / Female / Humans Idioma: En Año: 2022 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias de la Mama / G-Cuádruplex / Antineoplásicos Límite: Animals / Female / Humans Idioma: En Año: 2022 Tipo del documento: Article