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An exit beyond the pharmacophore model for 5-HT6R agents - a new strategy to gain dual 5-HT6/5-HT2A action for triazine derivatives with procognitive potential.
Kucwaj-Brysz, Katarzyna; Ali, Wesam; Kurczab, Rafal; Sudol-Talaj, Sylwia; Wilczynska-Zawal, Natalia; Jastrzebska-Wiesek, Magdalena; Satala, Grzegorz; Mordyl, Barbara; Zeslawska, Ewa; Czarnota, Kinga; Latacz, Gniewomir; Partyka, Anna; Wesolowska, Anna; Nitek, Wojciech; Handzlik, Jadwiga.
Afiliación
  • Kucwaj-Brysz K; Department of Technology and Biotechnology of Drugs, Faculty of Pharmacy, Jagiellonian University, Medical College, Medyczna 9, PL 30-688 Kraków, Poland.
  • Ali W; Department of Technology and Biotechnology of Drugs, Faculty of Pharmacy, Jagiellonian University, Medical College, Medyczna 9, PL 30-688 Kraków, Poland; Division of Bioorganic Chemistry, School of Pharmacy, Saarland University, Campus B 2.1, D-66123 Saarbruecken, Germany.
  • Kurczab R; Department of Medicinal Chemistry, Maj Institute of Pharmacology, Polish Academy of Sciences, Smetna 12, PL 31-343 Kraków, Poland.
  • Sudol-Talaj S; Department of Technology and Biotechnology of Drugs, Faculty of Pharmacy, Jagiellonian University, Medical College, Medyczna 9, PL 30-688 Kraków, Poland.
  • Wilczynska-Zawal N; Department of Clinical Pharmacy, Faculty of Pharmacy, Jagiellonian University, Medical College, Medyczna 9, PL 30-688 Kraków, Poland.
  • Jastrzebska-Wiesek M; Department of Clinical Pharmacy, Faculty of Pharmacy, Jagiellonian University, Medical College, Medyczna 9, PL 30-688 Kraków, Poland.
  • Satala G; Department of Medicinal Chemistry, Maj Institute of Pharmacology, Polish Academy of Sciences, Smetna 12, PL 31-343 Kraków, Poland.
  • Mordyl B; Department of Pharmacobiology, Faculty of Pharmacy, Jagiellonian University, Medical College, Medyczna 9, PL 30-688 Kraków, Poland.
  • Zeslawska E; Institute of Biology, Pedagogical University of Krakow, Podchorazych 2, PL 30-084 Kraków, Poland.
  • Agnieszka-Olejarz-Maciej; Department of Technology and Biotechnology of Drugs, Faculty of Pharmacy, Jagiellonian University, Medical College, Medyczna 9, PL 30-688 Kraków, Poland.
  • Czarnota K; Department of Technology and Biotechnology of Drugs, Faculty of Pharmacy, Jagiellonian University, Medical College, Medyczna 9, PL 30-688 Kraków, Poland.
  • Latacz G; Department of Technology and Biotechnology of Drugs, Faculty of Pharmacy, Jagiellonian University, Medical College, Medyczna 9, PL 30-688 Kraków, Poland.
  • Partyka A; Department of Clinical Pharmacy, Faculty of Pharmacy, Jagiellonian University, Medical College, Medyczna 9, PL 30-688 Kraków, Poland.
  • Wesolowska A; Department of Clinical Pharmacy, Faculty of Pharmacy, Jagiellonian University, Medical College, Medyczna 9, PL 30-688 Kraków, Poland.
  • Nitek W; Faculty of Chemistry, Jagiellonian University, Gronostajowa 2, PL 30-387 Kraków, Poland.
  • Handzlik J; Department of Technology and Biotechnology of Drugs, Faculty of Pharmacy, Jagiellonian University, Medical College, Medyczna 9, PL 30-688 Kraków, Poland. Electronic address: j.handzlik@uj.edu.pl.
Bioorg Chem ; 121: 105695, 2022 04.
Article en En | MEDLINE | ID: mdl-35228010
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Antagonistas de la Serotonina / Receptores de Serotonina Límite: Animals Idioma: En Año: 2022 Tipo del documento: Article
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Antagonistas de la Serotonina / Receptores de Serotonina Límite: Animals Idioma: En Año: 2022 Tipo del documento: Article