Phosphorothioate modification improves exon-skipping of antisense oligonucleotides based on sulfonyl phosphoramidates in <i>mdx</i> mouse myotubes.

Su, Yongdong; Raguraman, Prithi; Veedu, Rakesh N; Filichev, Vyacheslav V

Phosphorothioate modification improves exon-skipping of antisense oligonucleotides based on sulfonyl phosphoramidates in mdx mouse myotubes.

Su, Yongdong; Raguraman, Prithi; Veedu, Rakesh N; Filichev, Vyacheslav V.

Afiliación

Su Y; School of Natural Sciences, Massey University, Private Bag 11-222, 4442 Palmerston North, New Zealand. v.filichev@massey.ac.nz.
Raguraman P; Maurice Wilkins Centre for Molecular Biodiscovery, Auckland 1142, New Zealand.
Veedu RN; Centre for Molecular Medicine and Innovative Therapeutics, Murdoch University, Perth 6150, Australia. r.veedu@murdoch.edu.au.
Filichev VV; Perron Institute for Neurological and Translational Science, Perth 6150, Australia.

Org Biomol Chem ; 20(18): 3790-3797, 2022 05 11.

Article en En | MEDLINE | ID: mdl-35438707

Asunto(s)

Fibras Musculares Esqueléticas; Oligonucleótidos Antisentido; Amidas; Animales; Exones/genética; Ratones; Ratones Endogámicos mdx; Oligonucleótidos Antisentido/genética; Fosfatos; Ácidos Fosfóricos; Oligonucleótidos Fosforotioatos; ARN

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Oligonucleótidos Antisentido / Fibras Musculares Esqueléticas Límite: Animals Idioma: En Año: 2022 Tipo del documento: Article

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