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Protein Flexibility and Dissociation Pathway Differentiation Can Explain Onset of Resistance Mutations in Kinases.
Shekhar, Mrinal; Smith, Zachary; Seeliger, Markus A; Tiwary, Pratyush.
Afiliación
  • Shekhar M; Center for Development of Therapeutics, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
  • Smith Z; Biophysics Program and Institute for Physical Science and Technology, University of Maryland, College Park, MD 20742, USA.
  • Seeliger MA; Department of Pharmacological Sciences, Stony Brook University, Stony Brook, NY 11794-8651, USA.
  • Tiwary P; Department of Chemistry and Biochemistry and Institute for Physical Science and Technology, University of Maryland, College Park, MD 20742, USA.
Angew Chem Int Ed Engl ; 61(28): e202200983, 2022 07 11.
Article en En | MEDLINE | ID: mdl-35486370
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Piperazinas / Benzamidas Idioma: En Año: 2022 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Piperazinas / Benzamidas Idioma: En Año: 2022 Tipo del documento: Article