Kindlin-2 protects pancreatic ß cells through inhibiting NLRP3 inflammasome activation in diabetic mice.

Huang, Xiao-Ting; Xiong, Da-Yan; Xiao, Jin-Nan; Deng, Lang; Liu, Wei; Tang, Si-Yuan

Huang, Xiao-Ting; Xiong, Da-Yan; Xiao, Jin-Nan; Deng, Lang; Liu, Wei; Tang, Si-Yuan.

Afiliación

Huang XT; Xiangya Nursing School, Central South University, Changsha, Hunan, 410013, China.
Xiong DY; Xiangya Nursing School, Central South University, Changsha, Hunan, 410013, China.
Xiao JN; Xiangya Nursing School, Central South University, Changsha, Hunan, 410013, China.
Deng L; Xiangya Nursing School, Central South University, Changsha, Hunan, 410013, China.
Liu W; Xiangya Nursing School, Central South University, Changsha, Hunan, 410013, China. Electronic address: liuw079@csu.edu.cn.
Tang SY; Xiangya Nursing School, Central South University, Changsha, Hunan, 410013, China. Electronic address: sytang263@csu.edu.cn.

Biochem Biophys Res Commun ; 614: 1-8, 2022 07 23.

Article en En | MEDLINE | ID: mdl-35567938

Asunto(s)

Proteínas del Citoesqueleto; Diabetes Mellitus Experimental; Inflamasomas; Células Secretoras de Insulina; Animales; Citocinas/metabolismo; Proteínas del Citoesqueleto/genética; Proteínas del Citoesqueleto/metabolismo; Diabetes Mellitus Experimental/metabolismo; Glucosa/metabolismo; Inflamasomas/metabolismo; Células Secretoras de Insulina/metabolismo; Ratones; Ratones Endogámicos C57BL; Proteínas Musculares/metabolismo; Proteína con Dominio Pirina 3 de la Familia NLR/genética; Proteína con Dominio Pirina 3 de la Familia NLR/metabolismo

Palabras clave

Diabetes; Inflammation; Kindlin-2; NLRP3 inflammasome; ß-cells

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas del Citoesqueleto / Diabetes Mellitus Experimental / Células Secretoras de Insulina / Inflamasomas Límite: Animals Idioma: En Año: 2022 Tipo del documento: Article

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