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Mechanistic study of enantioselective Pd-catalyzed C(sp3)-H activation of thioethers involving two distinct stereomodels.
Saint-Denis, Tyler G; Lam, Nelson Y S; Chekshin, Nikita; Richardson, Paul F; Chen, Jason S; Elleraas, Jeff; Hesp, Kevin D; Schmitt, Daniel C; Lian, Yajing; Huh, Chan Woo; Yu, Jin-Quan.
Afiliación
  • Saint-Denis TG; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037.
  • Lam NYS; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037.
  • Chekshin N; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037.
  • Richardson PF; Oncology Medicinal Chemistry, Pfizer Global Research and Development, San Diego, CA 92121.
  • Chen JS; Automated Synthesis Facility, The Scripps Research Institute, La Jolla, CA 92037.
  • Elleraas J; Oncology Medicinal Chemistry, Pfizer Global Research and Development, San Diego, CA 92121.
  • Hesp KD; Medicine Design, Pfizer Global Research and Development, Groton, CT 06340.
  • Schmitt DC; Medicine Design, Pfizer Global Research and Development, Groton, CT 06340.
  • Lian Y; Medicine Design, Pfizer Global Research and Development, Groton, CT 06340.
  • Huh CW; Medicine Design, Pfizer Global Research and Development, Groton, CT 06340.
  • Yu JQ; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037.
ACS Catal ; 11(15): 9738-9753, 2021 Aug 06.
Article en En | MEDLINE | ID: mdl-35572380