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Drug screen in iPSC-Neurons identifies nucleoside analogs as inhibitors of (G4C2)n expression in C9orf72 ALS/FTD.
Czuppa, Mareike; Dhingra, Ashutosh; Zhou, Qihui; Schludi, Carina; König, Laura; Scharf, Elisabeth; Farny, Daniel; Dalmia, Anupriya; Täger, Joachim; Castillo-Lizardo, Melissa; Katona, Eszter; Mori, Kohji; Aumer, Tina; Schelter, Florian; Müller, Markus; Carell, Thomas; Kalliokoski, Tuomo; Messinger, Josef; Rizzu, Patrizia; Heutink, Peter; Edbauer, Dieter.
Afiliación
  • Czuppa M; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.
  • Dhingra A; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany. Electronic address: ashutosh.dhingra@dzne.de.
  • Zhou Q; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.
  • Schludi C; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.
  • König L; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.
  • Scharf E; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.
  • Farny D; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.
  • Dalmia A; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.
  • Täger J; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.
  • Castillo-Lizardo M; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.
  • Katona E; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.
  • Mori K; Psychiatry, Graduate School of Medicine, Osaka University, Suita, Japan.
  • Aumer T; Ludwig-Maximilians-University Munich, Faculty of Chemistry and Pharmacy, Munich, Germany.
  • Schelter F; Ludwig-Maximilians-University Munich, Faculty of Chemistry and Pharmacy, Munich, Germany.
  • Müller M; Ludwig-Maximilians-University Munich, Faculty of Chemistry and Pharmacy, Munich, Germany.
  • Carell T; Ludwig-Maximilians-University Munich, Faculty of Chemistry and Pharmacy, Munich, Germany.
  • Kalliokoski T; Orion Corporation Orion Pharma, Medicine Design, Espoo, Finland.
  • Messinger J; Orion Corporation Orion Pharma, Medicine Design, Espoo, Finland.
  • Rizzu P; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.
  • Heutink P; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany; Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.
  • Edbauer D; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany; Ludwig-Maximilians-University Munich, Graduate School of Systemic Neurosciences (GSN), Munich, Germany. Electronic address: dieter.edbauer@dzne.de.
Cell Rep ; 39(10): 110913, 2022 06 07.
Article en En | MEDLINE | ID: mdl-35675776
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Células Madre Pluripotentes Inducidas / Demencia Frontotemporal / Esclerosis Amiotrófica Lateral Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Año: 2022 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Células Madre Pluripotentes Inducidas / Demencia Frontotemporal / Esclerosis Amiotrófica Lateral Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Año: 2022 Tipo del documento: Article