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Low cerebrospinal fluid-to-plasma ratios of orally administered lenalidomide mediated by its low cell membrane permeability in patients with hematologic malignancies.
Ogiya, Daisuke; Murayama, Norie; Kamiya, Yusuke; Saito, Rie; Shiraiwa, Sawako; Suzuki, Rikio; Machida, Shinichiro; Tazume, Kei; Ando, Kiyoshi; Yamazaki, Hiroshi.
Afiliación
  • Ogiya D; Department of Hematology and Oncology, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa, 259-1193, Japan.
  • Murayama N; Department of Hematology, Isehara Kyodo Hospital, 345 Tanaka, Isehara, Kanagawa, 259-1187, Japan.
  • Kamiya Y; Laboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University, 3-3165 Higashi-tamagawa Gakuen, Machida, Tokyo, 194-8543, Japan.
  • Saito R; Laboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University, 3-3165 Higashi-tamagawa Gakuen, Machida, Tokyo, 194-8543, Japan.
  • Shiraiwa S; Laboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University, 3-3165 Higashi-tamagawa Gakuen, Machida, Tokyo, 194-8543, Japan.
  • Suzuki R; Department of Hematology and Oncology, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa, 259-1193, Japan.
  • Machida S; Department of Hematology and Oncology, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa, 259-1193, Japan.
  • Tazume K; Department of Hematology and Oncology, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa, 259-1193, Japan.
  • Ando K; Department of Hematology, Isehara Kyodo Hospital, 345 Tanaka, Isehara, Kanagawa, 259-1187, Japan.
  • Yamazaki H; Department of Hematology and Oncology, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa, 259-1193, Japan.
Ann Hematol ; 101(9): 2013-2019, 2022 Sep.
Article en En | MEDLINE | ID: mdl-35732975
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Hematológicas / Mieloma Múltiple Límite: Animals / Female / Humans / Pregnancy Idioma: En Año: 2022 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Hematológicas / Mieloma Múltiple Límite: Animals / Female / Humans / Pregnancy Idioma: En Año: 2022 Tipo del documento: Article