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The HHIP-AS1 lncRNA promotes tumorigenicity through stabilization of dynein complex 1 in human SHH-driven tumors.
Bartl, Jasmin; Zanini, Marco; Bernardi, Flavia; Forget, Antoine; Blümel, Lena; Talbot, Julie; Picard, Daniel; Qin, Nan; Cancila, Gabriele; Gao, Qingsong; Nath, Soumav; Koumba, Idriss Mahoungou; Wolter, Marietta; Kuonen, François; Langini, Maike; Beez, Thomas; Munoz, Christopher; Pauck, David; Marquardt, Viktoria; Yu, Hua; Souphron, Judith; Korsch, Mascha; Mölders, Christina; Berger, Daniel; Göbbels, Sarah; Meyer, Frauke-Dorothee; Scheffler, Björn; Rotblat, Barak; Diederichs, Sven; Ramaswamy, Vijay; Suzuki, Hiromishi; Oro, Anthony; Stühler, Kai; Stefanski, Anja; Fischer, Ute; Leprivier, Gabriel; Willbold, Dieter; Steger, Gerhard; Buell, Alexander; Kool, Marcel; Lichter, Peter; Pfister, Stefan M; Northcott, Paul A; Taylor, Michael D; Borkhardt, Arndt; Reifenberger, Guido; Ayrault, Olivier; Remke, Marc.
Afiliación
  • Bartl J; Division of Pediatric Neuro-Oncogenomics, German Cancer Research Center (DKFZ), Heidelberg, Germany, and German Cancer Consortium (DKTK), partner site Essen/Düsseldorf, Düsseldorf, Germany. jasmin.bartl@ini-research.org.
  • Zanini M; Department of Pediatric Oncology, Hematology, and Clinical Immunology, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany, and DKTK, partner site Essen/Düsseldorf, Düsseldorf, Germany. jasmin.bartl@ini-research.org.
  • Bernardi F; Institute of Neuropathology, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany, DKTK, partner site Essen/Düsseldorf, Düsseldorf, Germany. jasmin.bartl@ini-research.org.
  • Forget A; Group for Interdisciplinary Neurobiology and Immunology-INI-research, Institute of Zoology University of Hamburg, Hamburg, Germany. jasmin.bartl@ini-research.org.
  • Blümel L; Institut Curie, PSL Research University, CNRS UMR, INSERM, Orsay, France.
  • Talbot J; Université Paris Sud, Université Paris-Saclay, CNRS UMR, INSERM U, Orsay, France.
  • Picard D; Institut Curie, PSL Research University, CNRS UMR, INSERM, Orsay, France.
  • Qin N; Université Paris Sud, Université Paris-Saclay, CNRS UMR, INSERM U, Orsay, France.
  • Cancila G; Institut Curie, PSL Research University, CNRS UMR, INSERM, Orsay, France.
  • Gao Q; Université Paris Sud, Université Paris-Saclay, CNRS UMR, INSERM U, Orsay, France.
  • Nath S; Division of Pediatric Neuro-Oncogenomics, German Cancer Research Center (DKFZ), Heidelberg, Germany, and German Cancer Consortium (DKTK), partner site Essen/Düsseldorf, Düsseldorf, Germany.
  • Koumba IM; Department of Pediatric Oncology, Hematology, and Clinical Immunology, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany, and DKTK, partner site Essen/Düsseldorf, Düsseldorf, Germany.
  • Wolter M; Institute of Neuropathology, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany, DKTK, partner site Essen/Düsseldorf, Düsseldorf, Germany.
  • Kuonen F; Institut Curie, PSL Research University, CNRS UMR, INSERM, Orsay, France.
  • Langini M; Université Paris Sud, Université Paris-Saclay, CNRS UMR, INSERM U, Orsay, France.
  • Beez T; Division of Pediatric Neuro-Oncogenomics, German Cancer Research Center (DKFZ), Heidelberg, Germany, and German Cancer Consortium (DKTK), partner site Essen/Düsseldorf, Düsseldorf, Germany.
  • Munoz C; Department of Pediatric Oncology, Hematology, and Clinical Immunology, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany, and DKTK, partner site Essen/Düsseldorf, Düsseldorf, Germany.
  • Pauck D; Institute of Neuropathology, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany, DKTK, partner site Essen/Düsseldorf, Düsseldorf, Germany.
  • Marquardt V; Division of Pediatric Neuro-Oncogenomics, German Cancer Research Center (DKFZ), Heidelberg, Germany, and German Cancer Consortium (DKTK), partner site Essen/Düsseldorf, Düsseldorf, Germany.
  • Yu H; Department of Pediatric Oncology, Hematology, and Clinical Immunology, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany, and DKTK, partner site Essen/Düsseldorf, Düsseldorf, Germany.
  • Souphron J; Institute of Neuropathology, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany, DKTK, partner site Essen/Düsseldorf, Düsseldorf, Germany.
  • Korsch M; Institut Curie, PSL Research University, CNRS UMR, INSERM, Orsay, France.
  • Mölders C; Université Paris Sud, Université Paris-Saclay, CNRS UMR, INSERM U, Orsay, France.
  • Berger D; St Jude Children's Research Hospital, Memphis, TN, USA.
  • Göbbels S; Institut für Physikalische Biologie and Biological-Medical Research Center (BMFZ), Heinrich Heine University, Düsseldorf, Germany.
  • Meyer FD; IBI- (Strukturbiochemie) and JuStruct, Forschungszentrum Jülich, Jülich, Germany.
  • Scheffler B; Department of Pediatric Oncology, Hematology, and Clinical Immunology, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany, and DKTK, partner site Essen/Düsseldorf, Düsseldorf, Germany.
  • Rotblat B; Institute of Neuropathology, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany, DKTK, partner site Essen/Düsseldorf, Düsseldorf, Germany.
  • Diederichs S; Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA, USA.
  • Ramaswamy V; Department of Dermatology and Venereology, Hôpital de Beaumont, Lausanne University Hospital Center, CH- Lausanne, Lausanne, Switzerland.
  • Suzuki H; Institute for Molecular Medicine, Proteome Research, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany.
  • Oro A; Department of Neurosurgery, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany.
  • Stühler K; Department of Neurosurgery, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany.
  • Stefanski A; Division of Pediatric Neuro-Oncogenomics, German Cancer Research Center (DKFZ), Heidelberg, Germany, and German Cancer Consortium (DKTK), partner site Essen/Düsseldorf, Düsseldorf, Germany.
  • Fischer U; Department of Pediatric Oncology, Hematology, and Clinical Immunology, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany, and DKTK, partner site Essen/Düsseldorf, Düsseldorf, Germany.
  • Leprivier G; Institute of Neuropathology, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany, DKTK, partner site Essen/Düsseldorf, Düsseldorf, Germany.
  • Willbold D; Division of Pediatric Neuro-Oncogenomics, German Cancer Research Center (DKFZ), Heidelberg, Germany, and German Cancer Consortium (DKTK), partner site Essen/Düsseldorf, Düsseldorf, Germany.
  • Steger G; Department of Pediatric Oncology, Hematology, and Clinical Immunology, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany, and DKTK, partner site Essen/Düsseldorf, Düsseldorf, Germany.
  • Buell A; Institute of Neuropathology, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany, DKTK, partner site Essen/Düsseldorf, Düsseldorf, Germany.
  • Kool M; Institut Curie, PSL Research University, CNRS UMR, INSERM, Orsay, France.
  • Lichter P; Université Paris Sud, Université Paris-Saclay, CNRS UMR, INSERM U, Orsay, France.
  • Pfister SM; Institut Curie, PSL Research University, CNRS UMR, INSERM, Orsay, France.
  • Northcott PA; Université Paris Sud, Université Paris-Saclay, CNRS UMR, INSERM U, Orsay, France.
  • Taylor MD; Division of Pediatric Neuro-Oncogenomics, German Cancer Research Center (DKFZ), Heidelberg, Germany, and German Cancer Consortium (DKTK), partner site Essen/Düsseldorf, Düsseldorf, Germany.
  • Borkhardt A; Department of Pediatric Oncology, Hematology, and Clinical Immunology, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany, and DKTK, partner site Essen/Düsseldorf, Düsseldorf, Germany.
  • Reifenberger G; Institute of Neuropathology, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany, DKTK, partner site Essen/Düsseldorf, Düsseldorf, Germany.
  • Ayrault O; Division of Pediatric Neuro-Oncogenomics, German Cancer Research Center (DKFZ), Heidelberg, Germany, and German Cancer Consortium (DKTK), partner site Essen/Düsseldorf, Düsseldorf, Germany.
  • Remke M; Department of Pediatric Oncology, Hematology, and Clinical Immunology, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany, and DKTK, partner site Essen/Düsseldorf, Düsseldorf, Germany.
Nat Commun ; 13(1): 4061, 2022 07 13.
Article en En | MEDLINE | ID: mdl-35831316
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Cerebelosas / MicroARNs / ARN Largo no Codificante / Meduloblastoma Límite: Animals / Humans Idioma: En Año: 2022 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Cerebelosas / MicroARNs / ARN Largo no Codificante / Meduloblastoma Límite: Animals / Humans Idioma: En Año: 2022 Tipo del documento: Article