Estrone-Conjugated PEGylated Liposome Co-Loaded Paclitaxel and Carboplatin Improve Anti-Tumor Efficacy in Ovarian Cancer and Reduce Acute Toxicity of Chemo-Drugs.

Tang, Huan; Xie, Yizhuo; Zhu, Ming; Jia, Juan; Liu, Rui; Shen, Yujia; Zheng, Yucui; Guo, Xin; Miao, Dongfanghui; Pei, Jin

Tang, Huan; Xie, Yizhuo; Zhu, Ming; Jia, Juan; Liu, Rui; Shen, Yujia; Zheng, Yucui; Guo, Xin; Miao, Dongfanghui; Pei, Jin.

Afiliación

Tang H; Department of Biopharmacy, School of Pharmaceutical Sciences, Jilin University, Changchun, People's Republic of China.
Xie Y; Department of Biopharmacy, School of Pharmaceutical Sciences, Jilin University, Changchun, People's Republic of China.
Zhu M; Department of Biopharmacy, School of Pharmaceutical Sciences, Jilin University, Changchun, People's Republic of China.
Jia J; Department of Biopharmacy, School of Pharmaceutical Sciences, Jilin University, Changchun, People's Republic of China.
Liu R; Department of Biopharmacy, School of Pharmaceutical Sciences, Jilin University, Changchun, People's Republic of China.
Shen Y; Department of Biopharmacy, School of Pharmaceutical Sciences, Jilin University, Changchun, People's Republic of China.
Zheng Y; Department of Biopharmacy, School of Pharmaceutical Sciences, Jilin University, Changchun, People's Republic of China.
Guo X; Department of Biopharmacy, School of Pharmaceutical Sciences, Jilin University, Changchun, People's Republic of China.
Miao D; Department of Biopharmacy, School of Pharmaceutical Sciences, Jilin University, Changchun, People's Republic of China.
Pei J; Department of Biopharmacy, School of Pharmaceutical Sciences, Jilin University, Changchun, People's Republic of China.

Int J Nanomedicine ; 17: 3013-3041, 2022.

Article en En | MEDLINE | ID: mdl-35836838

Asunto(s)

Antineoplásicos; Neoplasias Ováricas; Animales; Antineoplásicos/uso terapéutico; Antineoplásicos/toxicidad; Carboplatino/uso terapéutico; Carboplatino/toxicidad; Carcinoma Epitelial de Ovario/tratamiento farmacológico; Línea Celular Tumoral; Sistemas de Liberación de Medicamentos/métodos; Estrona/uso terapéutico; Femenino; Humanos; Liposomas/uso terapéutico; Ratones; Ratones Endogámicos ICR; Neoplasias Ováricas/tratamiento farmacológico; Paclitaxel/uso terapéutico; Polietilenglicoles/química; Distribución Tisular

Palabras clave

combination therapy; drug delivery system; estrogen receptor; liposome; ovarian cancer

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Ováricas / Antineoplásicos Límite: Animals / Female / Humans Idioma: En Año: 2022 Tipo del documento: Article

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