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Blocking CHOP-dependent TXNIP shuttling to mitochondria attenuates albuminuria and mitigates kidney injury in nephrotic syndrome.
Park, Sun-Ji; Kim, Yeawon; Li, Chuang; Suh, Junwoo; Sivapackiam, Jothilingam; Goncalves, Tassia M; Jarad, George; Zhao, Guoyan; Urano, Fumihiko; Sharma, Vijay; Chen, Ying Maggie.
Afiliación
  • Park SJ; Division of Nephrology, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110.
  • Kim Y; Division of Nephrology, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110.
  • Li C; Division of Nephrology, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110.
  • Suh J; Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH 44106.
  • Sivapackiam J; Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO 63110.
  • Goncalves TM; Department of Neuroscience, Washington University School of Medicine, St. Louis, MO 63110.
  • Jarad G; Division of Nephrology, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110.
  • Zhao G; Department of Neuroscience, Washington University School of Medicine, St. Louis, MO 63110.
  • Urano F; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110.
  • Sharma V; Division of Endocrinology, Metabolism, and Lipid Research, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110.
  • Chen YM; Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO 63110.
Proc Natl Acad Sci U S A ; 119(35): e2116505119, 2022 08 30.
Article en En | MEDLINE | ID: mdl-35994650
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Tiorredoxinas / Proteínas Portadoras / Albuminuria / Factor de Transcripción CHOP / Riñón / Mitocondrias / Síndrome Nefrótico Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Año: 2022 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Tiorredoxinas / Proteínas Portadoras / Albuminuria / Factor de Transcripción CHOP / Riñón / Mitocondrias / Síndrome Nefrótico Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Año: 2022 Tipo del documento: Article