Nascent transcriptome reveals orchestration of zygotic genome activation in early embryogenesis.

Chen, Hui; Good, Matthew C

Chen, Hui; Good, Matthew C.

Afiliación

Chen H; Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Good MC; Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Bioengineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: mattgood@pennmedicine.upenn.edu.

Curr Biol ; 32(19): 4314-4324.e7, 2022 10 10.

Article en En | MEDLINE | ID: mdl-36007528

Asunto(s)

Transcriptoma; Cigoto; Cicloheximida/metabolismo; Desarrollo Embrionario/genética; Uridina/metabolismo; Cigoto/metabolismo

Palabras clave

5-ethynyl uridine; DNA:cytoplasm ratio; cell size gradient; cell-cycle elongation; click chemistry; early embryogenesis; germ layer; nascent transcription; spatiotemporal patterning; zygotic genome activation

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Cigoto / Transcriptoma Idioma: En Año: 2022 Tipo del documento: Article

Texto completo

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PubMed Links

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Cigoto / Transcriptoma Idioma: En Año: 2022 Tipo del documento: Article