SLC6A14 facilitates epithelial cell ferroptosis via the C/EBPß-PAK6 axis in ulcerative colitis.

Chen, Yanjun; Yan, Wenying; Chen, Yuqi; Zhu, Jinghan; Wang, Jiayu; Jin, Haiyan; Wu, Hongya; Zhang, Guangbo; Zhan, Shenghua; Xi, Qinhua; Shi, Tongguo; Chen, Weichang

Chen, Yanjun; Yan, Wenying; Chen, Yuqi; Zhu, Jinghan; Wang, Jiayu; Jin, Haiyan; Wu, Hongya; Zhang, Guangbo; Zhan, Shenghua; Xi, Qinhua; Shi, Tongguo; Chen, Weichang.

Afiliación

Chen Y; Jiangsu Institute of Clinical Immunology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Yan W; Department of Gastroenterology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Chen Y; Center for Systems Biology, Department of Bioinformatics, School of Biology and Basic Medical Sciences, Soochow University, Suzhou, China.
Zhu J; Jiangsu Institute of Clinical Immunology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Wang J; Department of Gastroenterology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Jin H; Jiangsu Institute of Clinical Immunology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Wu H; Department of Gastroenterology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Zhang G; Jiangsu Institute of Clinical Immunology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Zhan S; Department of Gastroenterology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Xi Q; Jiangsu Institute of Clinical Immunology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Shi T; Jiangsu Institute of Clinical Immunology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Chen W; Jiangsu Institute of Clinical Immunology, The First Affiliated Hospital of Soochow University, Suzhou, China.

Cell Mol Life Sci ; 79(11): 563, 2022 Oct 22.

Article en En | MEDLINE | ID: mdl-36272033

Asunto(s)

Colitis Ulcerosa; Ferroptosis; Humanos; Proteína beta Potenciadora de Unión a CCAAT/genética; Proteína beta Potenciadora de Unión a CCAAT/metabolismo; Colitis Ulcerosa/genética; Ciclooxigenasa 2; Células CACO-2; Ferroptosis/genética; Células Epiteliales/metabolismo; Quinasas p21 Activadas/genética; Quinasas p21 Activadas/metabolismo; Sistemas de Transporte de Aminoácidos

Palabras clave

C/EBPß; Ferroptosis; PAK6; SLC6A14; Ulcerative colitis

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Colitis Ulcerosa / Ferroptosis Límite: Humans Idioma: En Año: 2022 Tipo del documento: Article

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Colitis Ulcerosa / Ferroptosis Límite: Humans Idioma: En Año: 2022 Tipo del documento: Article